Biological Information
Family:
Transporter
Class:
ATPase
Protein Name:
Na/K ATPase
Uniprot Number:
P05023
Gene Name:
ATP1A1
Gene ID:
476
Organism:
Pig
Tissue:
Brain
Assay Information
Assay Type:
Biochemical
Assay Sub Type:
Enzymatic
Functional Mode:
Antagonist
Detection Method:
Spectrophotometric
Testing Information
Substrate:
ATP (2 mM)
Incubation:
60 min at 37°C
Control Inhibitor:
ouabain
Test Concentration / Dose:
Eurofins will provide IC/EC50 calculation if 5 or more concentrations are selected.
Test Sample Requirements:
Minimum for 1) Screen: 60 μl of 10 mM stock -OR- 1 mg (pre-weighed) for 10µM final testing. 2) Dose Response: 90 μl of 10 mM stock -OR- 1 mg (pre-weighed) for a top concentration at 10 µM.
Minimum Order Quantity:
2
Turnaround Time
Standard:
15 Business Days
Reference Compound Data
Clinical Relevance
Therapeutic Area:
CNS/Addiction/Pain
Additional Information
Brand:
LeadHunter
Testing Location:
France - Celle L'Evescault
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