Cellular Disease Models for Human Data Prior to Clinical Trials

Gain Predictive Potential with Human Disease Models

Eurofins Discovery’s expert teams help you stay focused on the human biology that matters by testing the effect of your high-throughput screening hit, drug candidate, or specialized library with assays and services that move you in the right direction—discovery of safer and more efficacious medicines for patients.
 
Validated against clinical compounds, our Translational Biology Center of Excellence cell-based disease models provide reproducible data, actionable insights, and a smooth transition into our broader portfolio of services. These models serve a variety of strategies from discovery to repurposing, and from individual to combination therapies.
 
Our cell migration assays – available for neurite outgrowth, angiogenesis, and wound healing applications – reveal morphological changes supported by high content analysis for investigations of therapeutic impact on cell motility.
 
Discover the benefits of our BioMAP® Platform to provide your team with an unbiased, target-agnostic and data-driven approach to understanding mono- or combination therapy influences on human biological systems and translational biomarkers. Validated with clinically approved drugs and known test agents, our BioMAP Platform is powered by human, primary cell-based disease models, a Reference Database of 4,500+ molecules, data analytics, and expert interpretation to provide you with actionable insights.
 
We’ve been a global leader in human phenotypic drug discovery services for over 20 years—advancing candidate pipelines for over 500 clients. We’re here to help get you to the finish line.

Key Areas

Address complex biology with wound healing, neurite outgrowth and angiogenesis assays.

Unique human immune response models for efficacy and safety.

Analytics-driven similarity search for in-depth assessment of candidates on a broad set of tissue and disease biology.

Model pulmonary, renal, and tissue fibrotic disease with biomarkers of matrix integrity, tissue remodeling, and chronic inflammation.

Human tumor microenvironment models to assess oncology and immuno-oncology potential in the context of host tissue. Also for combination studies.

Identify translational biomarkers and benchmark to seven standards-of-care reference drugs in a platform amenable to test agent screening.

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