CENPE Human PPP1R Enzymatic LeadHunter Assay - FR

Background Information:

Centromere Protein E (CENP-E), a kinesin-like motor protein that plays an active role of the microtubule-chromosome linkage, is essential for bipolar spindle formation and involved in mitosis. The mitotic arrest is proposed to be one of tumor inhibition. Inhibition of CENP-E is known to cause mitotic arrest, inhibitor of CENP-E kinesin may be useful in the treatment of various cancers.

Family:

DNA Repair & Mitotic Regulation

Sub Family:

PPP1R

Protein Name:

CENPE

Uniprot Number:

Q02224

Protein Aliases:

protein phosphatase 1, regulatory subunit 61

Gene Name:

CENPE

Gene ID:

1062

Gene Aliases:

KIF10|PPP1R61

Accession Number:

XM_011531544

Organism:

Human

Construct Details:

Recombinant