Biological Information

Family:

GPCR

Sub Family:

Galanin

Class:

Class A

Protein Name:

GAL2

Uniprot Number:

O43603

Protein Aliases:

GALR-2

Gene Name:

GALR2

Gene ID:

8811

Gene Aliases:

GALNR2

Accession Number:

XM_011525427

Organism:

Human

Construct Details:

Recombinant

Assay Information

Assay Type:

Biochemical

Assay Sub Type:

Binding

Detection Method:

Radiometric

Measured Response:

Scintillation

Testing Information

Ligand:

[125I]galanin

Ligand Kd (nM):

0.63

Ligand Concentration:

0.05 nM

Non Specific:

1 µM Galanin

Incubation:

120 min at RT

Control Inhibitor:

galanine porcine

Test Concentration / Dose:

Eurofins will provide IC/EC50 calculation if 5 or more concentrations are selected.

Test Sample Requirements:

Minimum for 1) Screen: 60 µl of 10 mM stock -OR- 1 mg (pre-weighed) for 10µM final testing. 2) Dose Response: 90 µl of 10 mM stock -OR- 1 mg (pre-weighed) for a top concentration at 10 µM.

Minimum Order Quantity:

2

Turnaround Time

Standard:

10 Business Days

Reference Compound Data

PubChem ID

16129686

Name

porcine galanin

Measurement

0.45nM - IC50

PubChem ID

Name

M15

Measurement

0.02nM - IC50

PubChem ID

Name

C7

Measurement

1.37nM - IC50

Clinical Relevance

Therapeutic Area:

CNS/Addiction/Pain

Additional Information

Brand:

LeadHunter

Testing Location:

France - Celle L'Evescault

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