S1P2 Human Lysophospholipid (S1P) GPCR Cell Based Antagonist Calcium Flux LeadHunter Assay - FR
OVERVIEW
DOCUMENTS/REFERENCES
Biological Information
Family:
GPCR
Sub Family:
Lysophospholipid (S1P)
Class:
Class A
Protein Name:
S1P2
Uniprot Number:
O95136
Protein Aliases:
EDG5|Endothelial differentiation G-protein coupled receptor 5|Sphingosine 1-phosphate receptor Edg-5|S1P receptor Edg-5
Gene Name:
S1PR2
Gene ID:
9294
Gene Aliases:
Gpcr13|H218|AGR16
Accession Number:
NM_004230
Organism:
Human
Construct Details:
Recombinant
Cell Type:
CHO-K1
Assay Information
Assay Type:
Functional
Assay Sub Type:
Cell Based
Functional Mode:
Antagonist
Detection Method:
Fluorimetry
Measured Response:
Fluorescence
Testing Information
Incubation:
RT
Control Inhibitor:
JTE 013
Control Activator:
Sphingosine 1-phosphate (S1P) (30 nM)
Test Concentration / Dose:
Eurofins will provide IC/EC50 calculation if 5 or more concentrations are selected.
Test Sample Requirements:
Minimum for 1) Screen: 70 µL of 10 mM stock -OR- 1 mg (pre-weighed) for 10µM finµL testing. 2) Dose Response: 90 µL of 10 mM stock -OR- 1 mg (pre-weighed) for a top concentration at 10 µM.
Minimum Order Quantity:
16
Turnaround Time
Standard:
15 Business Days
Reference Compound Data
Clinical Relevance
Therapeutic Area:
Inflammation/Allergy
Additional Information
Brand:
LeadHunter
Testing Location:
France - Celle L'Evescault
RELATED SOLUTIONS
S1P2 Human Lysophospholipid (S1P) GPCR Cell Based Agonist Calcium Flux LeadHunter Assay - FR
Item: 2133
S1P2 Human Lysophospholipid (S1P) GPCR Cell Based Agonist & Antagonist Calcium Flux LeadHunter Assay - FR
Item: G026
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