Biological Information

Family:

GPCR

Sub Family:

Lysophospholipid (S1P)

Class:

Class A

Protein Name:

S1P2

Uniprot Number:

O95136

Protein Aliases:

EDG5|Endothelial differentiation G-protein coupled receptor 5|Sphingosine 1-phosphate receptor Edg-5|S1P receptor Edg-5

Gene Name:

S1PR2

Gene ID:

9294

Gene Aliases:

Gpcr13|H218|AGR16

Accession Number:

NM_004230

Organism:

Human

Construct Details:

Recombinant

Cell Type:

CHO-K1

Assay Information

Assay Type:

Functional

Assay Sub Type:

Cell Based

Functional Mode:

Agonist

Detection Method:

Fluorimetry

Measured Response:

Fluorescence

Testing Information

Incubation:

RT

Control Activator:

Sphingosine 1-phosphate

Test Concentration / Dose:

Eurofins will provide IC/EC50 calculation if 5 or more concentrations are selected.

Test Sample Requirements:

Minimum for 1) Screen: 70 µL of 10 mM stock -OR- 1 mg (pre-weighed) for 10µM finµL testing. 2) Dose Response: 90 µL of 10 mM stock -OR- 1 mg (pre-weighed) for a top concentration at 10 µM.

Minimum Order Quantity:

16

Turnaround Time

Standard:

15 Business Days

Reference Compound Data

PubChem ID

122121

Name

phytosphingosine

Measurement

- EC50

PubChem ID

4077460

Name

SEW2871

Measurement

- EC50

PubChem ID

5283560

Name

Sphingosine 1-phosphate

Measurement

12nM - EC50

Clinical Relevance

Therapeutic Area:

Inflammation/Allergy

Additional Information

Brand:

LeadHunter

Testing Location:

France - Celle L'Evescault

RELATED SOLUTIONS

Item: 2135
Item: G026