alpha1D Human Adrenoceptor GPCR Binding Antagonist Radioligand LeadHunter Assay - FR

Background Information:

Adrenoreceptors belong to the superfamily of G protein-coupled seven transmembrane proteins. G-protein-coupled receptors constitute one of the major signal transduction systems in eukaryotic cells. Coding sequences for these receptors, in those regions believed to contribute to the agonist-antagonist binding site, are strongly conserved across mammalian species. Adrenoreceptors are found in most peripheral tissue and within the central nervous system.

Family:

GPCR

Sub Family:

Adrenoceptor

Class:

Class A

Protein Name:

alpha1D

Uniprot Number:

P25100

Protein Aliases:

Alpha-1D adrenoreceptor|Alpha-1D adrenoceptor|Alpha-adrenergic receptor 1a

Gene Name:

ADRA1D

Gene ID:

146

Gene Aliases:

ADRA1R|ADRA1A|ADRA1

Accession Number:

NM_000678

Organism:

Human

Construct Details:

Recombinant