OVERVIEW
DOCUMENTS/REFERENCES
Biological Information
Family:
Epigenetic
Sub Family:
Histone Acetyltransferase (HAT)
Class:
Writer
Protein Name:
PCAF
Uniprot Number:
Q92831
Protein Aliases:
Histone acetyltransferase PCAF|Histone acetylase PCAF|Lysine acetyltransferase 2B|P300/CBP-associated factor|P/CAF
Gene Name:
KAT2B
Gene ID:
8850
Gene Aliases:
P/CAF|GCN5|GCN5L
Accession Number:
NM_003884
Organism:
Human
Construct Details:
Recombinant
Assay Information
Assay Type:
Biochemical
Assay Sub Type:
Enzymatic
Functional Mode:
Antagonist
Detection Method:
Radiometric
Measured Response:
Scintillation
Testing Information
Substrate:
histone H3 full length (25nM)
Tracer:
[3H] Acetyl CoenzymeA (25 nM)
Incubation:
10 min at 22°C
Control Inhibitor:
Garcinol
Test Concentration / Dose:
Eurofins will provide IC/EC50 calculation if 5 or more concentrations are selected.
Test Sample Requirements:
Minimum for 1) Screen: 60 μl of 10 mM stock -OR- 1 mg (pre-weighed) for 10µM final testing. 2) Dose Response: 90 μl of 10 mM stock -OR- 1 mg (pre-weighed) for a top concentration at 10 µM.
Minimum Order Quantity:
10
Turnaround Time
Standard:
15 Business Days
Reference Compound Data
Additional Information
Brand:
LeadHunter
Testing Location:
France - Celle L'Evescault
Questions? Contact Us
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