Pancreatic Elastase 1 Pig Chymotrypsin Serine Peptidase Enzymatic LeadHunter Assay - TW

Background Information:

Pancreatic elastase 1, a serine proteinase, cleaves peptide bonds at the carbonyl end of amino acid residues with small hydrophobic side chains, such as glycine, valine, leucine, isoleucine, and particularly alanine. The wide specificity of elastase for non-aromatic uncharged side chains explains its unique ability to digest native elastin, a protein rich in aliphatic side chains. Pancreatic elastase 1 is also able to digest other proteins such as fibrin, hemoglobin, and casein, but not native collagen and keratin. Agents that inhibit pancreatic elastase may have clinical applications in treating chronic pancreatitis, cystic fibrosis, and pulmonary emphysema

Family:

Protease

Sub Family:

Chymotrypsin

Class:

Serine Peptidase

Protein Name:

Pancreatic Elastase 1

Uniprot Number:

P00772

Protein Aliases:

Elastase-1

Gene Name:

CELA1

Gene ID:

1990

Gene Aliases:

ELA1

Accession Number:

NM_001971

Organism:

Pig

Construct Details:

Endogenous