NT1 Human Neurotensin GPCR Cell Based Agonist IP1 LeadHunter Assay - TW

Background Information:

Neurotensin (NT) receptors belong to the superfamily of G protein-coupled receptors. Neurotensin NT1 an NT2 receptors have seven transmembrane domains, whereas NT3 has a single transmembrane domain. G-protein-coupled receptors constitute one of the major signal transduction systems in eukaryotic cells. Coding sequences for these receptors, in those regions believed to contribute to the agonist-antagonist binding site, are strongly conserved across mammalian species. Neurotensin NT receptors are widely distributed in the central nervous system and gastrointestinal tract.

Family:

GPCR

Sub Family:

Neurotensin

Class:

Class A

Protein Name:

NT1

Uniprot Number:

P30989

Protein Aliases:

NTR1|High-affinity levocabastine-insensitive neurotensin receptor|NTRH

Gene Name:

NTSR1

Gene ID:

4923

Gene Aliases:

NTR|NTRR

Accession Number:

XM_011528827

Organism:

Human

Construct Details:

Full Length, Recombinant

Cell Type:

CHO-K1