LH Human Glycoprotein Hormone GPCR Cell Based Agonist Arrestin LeadHunter Assay - US

Background Information:

PathHunter β-Arrestin GPCR cell lines are engineered to co-express the ProLink™ (PK) tagged GPCR and the Enzyme Acceptor (EA) tagged β-Arrestin. Activation of the GPCR-PK induces β-Arrestin-EA recruitment, forcing complementation of the two β-galactosidase enzyme fragments (EA and PK). The resulting functional enzyme hydrolyzes substrate to generate a chemiluminescent signal.

Family:

GPCR

Sub Family:

Glycoprotein Hormone

Class:

Class A

Coupling:

Gs

Protein Name:

LH

Uniprot Number:

P22888

Protein Aliases:

Luteinizing hormone receptor|LHR|LSH-R

Gene Name:

LHCGR

Gene ID:

3973

Gene Aliases:

LHR|LCGR|LGR2|ULG5|LGR2|LHRHR

Accession Number:

NM_000233

Organism:

Human

Cell Type:

CHO-K1