OVERVIEW
DOCUMENTS/REFERENCES
Biological Information
Background Information:
Solution instability can be a limitation for effective dosing and the in vivo efficacy of a therapeutic compound. Eurofins has a high-throughput assay to determine chemical stability in buffer and simulated biological fluids using LCMS analysis to quantify the percent compound remaining after incubation. Subsequently, the half-life (T1/2) is estimated from the slope of the initial linear range of the logarithmic curve of compound remaining (%) versus time, assuming first order kinetics.
Assay Information
Assay Type:
Physiochemical
Detection Method:
HPLC-MS/MS
Measured Response:
Peak Area Response
Testing Information
Substrate:
Test compound
Incubation:
60 min at 37°C
Turnaround Time
Standard:
15 Business Days
Additional Information
Brand:
Cerep
Testing Location:
USA - St Charles, MO
Questions? Contact Us
You can easily get in touch with a Eurofins Discovery Expert or get help from our Customer Service team. Reach out with questions, or to discuss your specific discovery challenges.
