Cathepsin G Human Chymotrypsin Serine Peptidase Enzymatic LeadHunter Assay - FR

Background Information:

The major neutral proteases of neutrophil granules are the serine proteases elastase and cathepsin G, a serine protease. The latter enzyme shows a strong preference for hydrophobic substrates. Since these enzymes degrade connective tissue and other proteins, inhibition of either one or both enzymes may be therapeutically beneficial in pathological conditions where neutrophils are implicated. Inhibitors of these enzymes are potentially useful for the treatment of rheumatoid arthritis, psoriasis, periodontitis and other inflammatory diseases.

Family:

Protease

Sub Family:

Chymotrypsin

Class:

Serine Peptidase

Protein Name:

Cathepsin G

Uniprot Number:

P08311

Gene Name:

CTSG

Gene ID:

1511

Gene Aliases:

CG

Accession Number:

NM_001911

Organism:

Human