OVERVIEW
DOCUMENTS/REFERENCES
Biological Information
Background Information:
This panel of assays is designed to determine the stability of a test compound with each of the common human recombinant UDP-glucuronosyl-transferase (UGT) isozymes in 96-well plate format. The test compound is quantified at five time points by HPLC-MS/MS analysis.
No. of Assays on Panel:
8
Assays on Panel:
Family
Glycosyltransferase
Name
Intrinsic Clearance (UGT2B7) - US
Item
1860
Protein
UGT2B7
Organism
Human
Assay Sub Type
Enzymatic
Family
Glycosyltransferase
Name
Intrinsic Clearance (UGT1A1) - US
Item
1861
Protein
UGT1A
Organism
Human
Assay Sub Type
Enzymatic
Family
Glycosyltransferase
Name
Intrinsic Clearance (UGT1A3) - US
Item
3162
Protein
UGT1A3
Organism
Human
Assay Sub Type
Enzymatic
Family
Glycosyltransferase
Name
Intrinsic Clearance (UGT1A6) - US
Item
3163
Protein
UGT1A6
Organism
Human
Assay Sub Type
Enzymatic
Family
Glycosyltransferase
Name
Intrinsic Clearance (UGT1A8) - US
Item
3165
Protein
UGT1A8
Organism
Human
Assay Sub Type
Enzymatic
Family
Glycosyltransferase
Name
Intrinsic Clearance (UGT1A9) - US
Item
3166
Protein
UGT1A9
Organism
Human
Assay Sub Type
Enzymatic
Family
Glycosyltransferase
Name
Intrinsic Clearance (UGT2B15) - US
Item
3169
Protein
UGT2B15
Organism
Human
Assay Sub Type
Enzymatic
Family
Glycosyltransferase
Name
Intrinsic Clearance (UGT1A4) - US
Item
3415
Protein
UGT1A4
Organism
Human
Assay Sub Type
Enzymatic
Family:
Glycosyltransferase
Sub Family:
UDP Glucuronosyltransferase
Protein Name:
UGT1A
Gene Name:
UGT1A
Gene ID:
7361
Gene Aliases:
UGT
Organism:
Human
Construct Details:
Full length, recombi
Assay Information
Assay Type:
Biochemical
Assay Sub Type:
Enzymatic
Detection Method:
HPLC-MS
Measured Response:
Peak Area Response
Testing Information
Test Sample Requirements:
Minimum for 1) Screen: 100 μl of 10 mM stock -OR- 1 to 2 mg (pre-weighed). 2) Dose Response: 250 μl of 10 mM stock -OR- 1.5 to 2 mg (pre-weighed).
Turnaround Time
Standard:
20 Business Days
Additional Information
Brand:
Cerep
Testing Location:
USA - St Charles, MO
RELATED SOLUTIONS
Intrinsic Clearance (UGT1A1) - US
Item: 1861
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