B1 Human Bradykinin GPCR Cell Based Agonist & Antagonist Calcium Flux LeadHunter Assay - FR

Background Information:

Bradykinin receptors belong to the superfamily of G protein-coupled seven transmembrane proteins. G-protein-coupled receptors constitute one of the major signal transduction systems in eukaryotic cells. Coding sequences for these receptors, in those regions believed to contribute to the agonist-antagonist binding site, are strongly conserved across mammalian species. Bradykinin receptors are found in most peripheral tissue and within the central nervous system.

No. of Assays on Panel:

2

Family:

GPCR

Sub Family:

Bradykinin

Class:

Class A

Protein Name:

B1

Uniprot Number:

P46663

Protein Aliases:

BK-1 receptor

Gene Name:

BDKRB1

Gene ID:

623

Gene Aliases:

BKR1|B1BKR|bradyb1

Organism:

Human

Cell Type:

CHO-K1