5-LO Human Lipoxygenase Enzymatic LeadHunter Assay - TW

Background Information:

5-Lipoxygenase catalyzes the oxidative metabolism of arachidonic acid to 5-hydroxyeicosatetraenoic acid (5-HETE), the initial reaction leading to formation of leukotrienes. Leukotrienes (LTs) are inflammatory mediators causing, for example, phagocyte chemotaxis and increased vascular permeability. Inhibition of LT biosynthesis may be beneficial in inflammatory diseases.

Family:

Lipid Metabolism

Sub Family:

Eicosanoid Turnover

Class:

Lipoxygenase

Protein Name:

5-LO

Uniprot Number:

P09917

Protein Aliases:

Arachidonate 5-lipoxygenase B, 5-LO

Gene Name:

ALOX5

Gene ID:

240

Gene Aliases:

5-LOX

Accession Number:

NM_000698

Organism:

Human

Construct Details:

Full Length, Recombinant