Biological Information

Family:

GPCR

Sub Family:

Calcium-Sensing

Class:

Class C

Protein Name:

CaS

Uniprot Number:

P41180

Gene Name:

CASR

Gene ID:

846

Gene Aliases:

FHH|NSHPT|GPRC2A

Accession Number:

NM_000388

Organism:

Human

Construct Details:

Recombinant

Cell Type:

HEK293

Assay Information

Assay Type:

Functional

Assay Sub Type:

Cell Based

Functional Mode:

Agonist

Detection Method:

Fluorimetry

Measured Response:

Fluorescence

Testing Information

Incubation:

RT

Control Activator:

Neomycin

Test Concentration / Dose:

Eurofins will provide IC/EC50 calculation if 5 or more concentrations are selected.

Test Sample Requirements:

Minimum for 1) Screen: 70 µL of 10 mM stock -OR- 1 mg (pre-weighed) for 10µM finµL testing. 2) Dose Response: 90 µL of 10 mM stock -OR- 1 mg (pre-weighed) for a top concentration at 10 µM.

Minimum Order Quantity:

16

Turnaround Time

Standard:

15 Business Days

Reference Compound Data

PubChem ID

1103

Name

Spermine

Measurement

49000nM - EC50

PubChem ID

8378

Name

Neomycin

Measurement

11000nM - EC50

PubChem ID

5284359

Name

CALCIUM CHLORIDE

Measurement

470000nM - EC50

PubChem ID

Name

gadolinium (III) chloride hexahydrate

Measurement

120000nM - EC50

Clinical Relevance

Adverse / Beneficial Action:

severe neonatal hyperparathyroidism

Additional Information

Brand:

LeadHunter

Testing Location:

France - Celle L'Evescault

RELATED SOLUTIONS

Item: 2146
Item: G010