Ubiquitin

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  • 23-039M - Smad7, 250 ug $2,626.50 Add To Cart Qty:
    The TGF-β signalling cascade regulates diverse cellular processes, including cell proliferation, differentiation, apoptosis, adhesion and migration. It plays a fundamental role in a number of different physiological and...
  • 23-041 - c-Cbl Protein, active, 10 ug $458.35 Add To Cart Qty:
    Intracellular signals mediated by receptor tyrosine kinases play a pivotal role in morphogenesis, cell fate determination and pathogenesis. c-Cbl is a ubiquitin ligase (E3) that facilitates the regulation of these pathways,...
  • 23-041-K - c-Cbl Protein, active
    Intracellular signals mediated by receptor tyrosine kinases play a pivotal role in morphogenesis, cell fate determination and pathogenesis. c-Cbl is a ubiquitin ligase (E3) that facilitates the regulation of these pathways,...
  • 23-041M - c-Cbl Protein, active, 250 ug $2,626.50 Add To Cart Qty:
    Intracellular signals mediated by receptor tyrosine kinases play a pivotal role in morphogenesis, cell fate determination and pathogenesis. c-Cbl is a ubiquitin ligase (E3) that facilitates the regulation of these pathways,...
  • 23-042 - Src Protein, 10 ug $458.35 Add To Cart Qty:
    Src is a ubiquitously expressed, non-receptor tyrosine kinase that plays a pivotal role in numerous cellular processes such as proliferation, migration, and transformation. Due to its critical function in regulating signal...
  • 23-042-K - Src Protein
    Src is a ubiquitously expressed, non-receptor tyrosine kinase that plays a pivotal role in numerous cellular processes such as proliferation, migration, and transformation. Due to its critical function in regulating signal...
  • 23-042M - Src Protein, 250 ug $2,626.50 Add To Cart Qty:
    Src is a ubiquitously expressed, non-receptor tyrosine kinase that plays a pivotal role in numerous cellular processes such as proliferation, migration, and transformation. Due to its critical function in regulating signal...
  • 23-043 - Kit Protein, 10 ug $458.35 Add To Cart Qty:
    Kit belongs to the family of type III receptor tyrosine kinases. It mediates the cellular response to stem cell factor and plays a major role in survival, expansion and differentiation of haematopoietic progenitor cells and...
  • 23-043-K - Kit Protein
    Kit belongs to the family of type III receptor tyrosine kinases. It mediates the cellular response to stem cell factor and plays a major role in survival, expansion and differentiation of haematopoietic progenitor cells and...
  • 23-043M - Kit Protein, 250 ug $2,626.50 Add To Cart Qty:
    Kit belongs to the family of type III receptor tyrosine kinases. It mediates the cellular response to stem cell factor and plays a major role in survival, expansion and differentiation of haematopoietic progenitor cells and...
  • 23-044 - VHL Protein Complex, Active, 10 ug $458.35 Add To Cart Qty:
    The VHL complex is a multi-subunit ubiquitin ligase composed of VHL, Elongin B, Elongin C, Cul2 and Rbx1. The VHL protein serves as the substrate recognition component and is linked by Elongin C to a heterodimeric Cul2/Rbx1...
  • 23-044-K - VHL Protein Complex, Active
    The VHL complex is a multi-subunit ubiquitin ligase composed of VHL, Elongin B, Elongin C, Cul2 and Rbx1. The VHL protein serves as the substrate recognition component and is linked by Elongin C to a heterodimeric Cul2/Rbx1...
  • 23-044M - VHL Protein Complex, Active, 250 ug $2,626.50 Add To Cart Qty:
    The VHL complex is a multi-subunit ubiquitin ligase composed of VHL, Elongin B, Elongin C, Cul2 and Rbx1. The VHL protein serves as the substrate recognition component and is linked by Elongin C to a heterodimeric Cul2/Rbx1...
  • 23-045 - HIF-1 alpha Protein, 10 ug $458.35 Add To Cart Qty:
    HIF-1α is the oxygen sensitive subunit of the hypoxia inducible factor HIF-1 which is an essential mediator of the cellular oxygen-signalling pathway. Under hypoxic conditions HIF-1α activates the transcription...
  • 23-045-K - HIF-1 alpha Protein
    HIF-1α is the oxygen sensitive subunit of the hypoxia inducible factor HIF-1 which is an essential mediator of the cellular oxygen-signalling pathway. Under hypoxic conditions HIF-1α activates the transcription...
  • 23-045M - HIF-1 alpha Protein, 250 ug $4,285.03 Add To Cart Qty:
    HIF-1α is the oxygen sensitive subunit of the hypoxia inducible factor HIF-1 which is an essential mediator of the cellular oxygen-signalling pathway. Under hypoxic conditions HIF-1α activates the transcription...
  • 23-046 - Parkin (c-Myc tagged) Protein, active, 10 ug $458.35 Add To Cart Qty:
    Parkin is an E3-ubiquitin ligase belonging to the RBR (RING – In Between RING – RING) family. Mutations in Parkin that result in a loss-of-function are the most frequent cause of familial Parkinson’s...
  • 23-046-K - Parkin (c-Myc tagged) Protein, active
    Parkin is an E3-ubiquitin ligase belonging to the RBR (RING – In Between RING – RING) family. Mutations in Parkin that result in a loss-of-function are the most frequent cause of familial Parkinson’s...
  • 23-046M - Parkin (c-Myc tagged) Protein, active, 250 ug $2,626.50 Add To Cart Qty:
    Parkin is an E3-ubiquitin ligase belonging to the RBR (RING – In Between RING – RING) family. Mutations in Parkin that result in a loss-of-function are the most frequent cause of familial Parkinson’s...
  • 23-047 - UbcH7 Protein, active, 10 ug $143.17 Add To Cart Qty:
    Ubiquitin-conjugating (E2) enzymes are characterized by the presence of a highly conserved ubiquitin-conjugating domain, which accommodates ATP-activated ubiquitin (Ub) via a covalently linked thioester on its active-site...
  • 23-047-K - UbcH7 Protein, active
    Ubiquitin-conjugating (E2) enzymes are characterized by the presence of a highly conserved ubiquitin-conjugating domain, which accommodates ATP-activated ubiquitin (Ub) via a covalently linked thioester on its active-site...
  • 23-047M - UbcH7 Protein, active, 250 ug $682.89 Add To Cart Qty:
    Ubiquitin-conjugating (E2) enzymes are characterized by the presence of a highly conserved ubiquitin-conjugating domain, which accommodates ATP-activated ubiquitin (Ub) via a covalently linked thioester on its active-site...
  • 23-048 - Parkin Protein, active, 10 ug $458.35 Add To Cart Qty:
    Parkin is an E3-ubiquitin ligase belonging to the RBR (RING – In Between RING – RING) family. Mutations in Parkin that result in a loss-of-function are the most frequent cause of familial Parkinson’s...
  • 23-048-K - Parkin Protein, active
    Parkin is an E3-ubiquitin ligase belonging to the RBR (RING – In Between RING – RING) family. Mutations in Parkin that result in a loss-of-function are the most frequent cause of familial Parkinson’s...
  • 23-048M - Parkin Protein, active, 250 ug $2,626.50 Add To Cart Qty:
    Parkin is an E3-ubiquitin ligase belonging to the RBR (RING – In Between RING – RING) family. Mutations in Parkin that result in a loss-of-function are the most frequent cause of familial Parkinson’s...
  • 23-049 - p38/JTV-1 Protein, 10 ug $458.35 Add To Cart Qty:
    p38/JTV-1 is a scaffold required for the assembly and stability of the multi-tRNA synthetase complex, an essential enzyme that ligates specific amino acids to tRNAs before protein synthesis. It plays a pivotal role in the...
  • 23-049-K - p38/JTV-1 Protein
    p38/JTV-1 is a scaffold required for the assembly and stability of the multi-tRNA synthetase complex, an essential enzyme that ligates specific amino acids to tRNAs before protein synthesis. It plays a pivotal role in the...
  • 23-049M - p38/JTV-1 Protein, 250 ug $2,626.50 Add To Cart Qty:
    p38/JTV-1 is a scaffold required for the assembly and stability of the multi-tRNA synthetase complex, an essential enzyme that ligates specific amino acids to tRNAs before protein synthesis. It plays a pivotal role in the...
  • 23-050 - CHIP Protein, active, 10 ug $458.35 Add To Cart Qty:
    CHIP is an E3 ubiquitin-protein ligase which targets misfolded chaperone substrates for proteasomal degradation. It contains multiple domains, including a tetratricopeptide repeat (TPR) domain that allows interaction with...
  • 23-050-K - CHIP Protein, active
    CHIP is an E3 ubiquitin-protein ligase which targets misfolded chaperone substrates for proteasomal degradation. It contains multiple domains, including a tetratricopeptide repeat (TPR) domain that allows interaction with...
  • 23-050M - CHIP Protein, active, 250 ug $2,626.50 Add To Cart Qty:
    CHIP is an E3 ubiquitin-protein ligase which targets misfolded chaperone substrates for proteasomal degradation. It contains multiple domains, including a tetratricopeptide repeat (TPR) domain that allows interaction with...
  • 23-051 - UbcH13/Uev1A Protein, active, 10 ug $211.91 Add To Cart Qty:
    Ubiquitin-conjugating (E2) enzymes are characterized by the presence of a highly conserved ubiquitin-conjugating domain which accommodates ATP-activated ubiquitin (Ub) via a covalently linked thioester onto its active-site...
  • 23-051-K - UbcH13/Uev1A Protein, active
    Ubiquitin-conjugating (E2) enzymes are characterized by the presence of a highly conserved ubiquitin-conjugating domain which accommodates ATP-activated ubiquitin (Ub) via a covalently linked thioester onto its active-site...
  • 23-051M - UbcH13/Uev1A Protein, active, 250 ug $682.89 Add To Cart Qty:
    Ubiquitin-conjugating (E2) enzymes are characterized by the presence of a highly conserved ubiquitin-conjugating domain which accommodates ATP-activated ubiquitin (Ub) via a covalently linked thioester onto its active-site...
  • 23-052 - Hsp70 Protein, 10 ug $458.35 Add To Cart Qty:
    Hsp70 proteins are central components of the cellular network of molecular chaperones. They assist in a wide range of processes, including the folding and assembly of newly synthesized proteins, refolding of misfolded and...
  • 23-052-K - Hsp70 Protein
    Hsp70 proteins are central components of the cellular network of molecular chaperones. They assist in a wide range of processes, including the folding and assembly of newly synthesized proteins, refolding of misfolded and...
  • 23-052M - Hsp70 Protein, 250 ug $2,626.50 Add To Cart Qty:
    Hsp70 proteins are central components of the cellular network of molecular chaperones. They assist in a wide range of processes, including the folding and assembly of newly synthesized proteins, refolding of misfolded and...
  • 23-053 - CHIP (c-Myc tagged) Protein, active, 10 ug $458.35 Add To Cart Qty:
    CHIP is an E3 ubiquitin-protein ligase which targets misfolded chaperone substrates for proteasomal degradation. It contains multiple domains, including a tetratricopeptide repeat (TPR) domain that allows interaction with...
  • 23-053-K - CHIP (c-Myc tagged) Protein, active
    CHIP is an E3 ubiquitin-protein ligase which targets misfolded chaperone substrates for proteasomal degradation. It contains multiple domains, including a tetratricopeptide repeat (TPR) domain that allows interaction with...
  • 23-053M - CHIP (c-Myc tagged) Protein, active, 250 ug $2,626.50 Add To Cart Qty:
    CHIP is an E3 ubiquitin-protein ligase which targets misfolded chaperone substrates for proteasomal degradation. It contains multiple domains, including a tetratricopeptide repeat (TPR) domain that allows interaction with...
  • 23-054 - MuRF1 Protein, active, 10 ug $449.08 Add To Cart Qty:
    Muscle atrophy is a debilitating and life threatening disorder. It is associated with a number of diseases including cancer, diabetes, chronic obstructive pulmonary disease and AIDS and is a natural consequence of inactivity...
  • 23-054-K - MuRF1 Protein, active
    Muscle atrophy is a debilitating and life threatening disorder. It is associated with a number of diseases including cancer, diabetes, chronic obstructive pulmonary disease and AIDS and is a natural consequence of inactivity...
  • 23-054M - MuRF1 Protein, active, 250 ug $2,575.00 Add To Cart Qty:
    Muscle atrophy is a debilitating and life threatening disorder. It is associated with a number of diseases including cancer, diabetes, chronic obstructive pulmonary disease and AIDS and is a natural consequence of inactivity...
  • 23-055 - Cardiac Troponin I, 10 ug $449.08 Add To Cart Qty:
    Troponin is a complex of three regulatory proteins (Troponin I, Troponin T and Troponin C). It is located on the actin filament and is essential for the calcium-mediated regulation of skeletal and cardiac muscle contraction...
  • 23-055-K - Cardiac Troponin I
    Troponin is a complex of three regulatory proteins (Troponin I, Troponin T and Troponin C). It is located on the actin filament and is essential for the calcium-mediated regulation of skeletal and cardiac muscle contraction...
  • 23-055M - Cardiac Troponin I, 250 ug $2,575.00 Add To Cart Qty:
    Troponin is a complex of three regulatory proteins (Troponin I, Troponin T and Troponin C). It is located on the actin filament and is essential for the calcium-mediated regulation of skeletal and cardiac muscle contraction...
  • 23-056 - XIAP, active, 10 ug $458.35 Add To Cart Qty:
    X-linked inhibitor of apoptosis (XIAP) is one of a group of intracellular proteins which have been shown to act as endogenous inhibitors of caspases, the enzymatic effectors of apoptosis. XIAP possesses a C-terminal RING...
  • 23-056-K - XIAP, active
    X-linked inhibitor of apoptosis (XIAP) is one of a group of intracellular proteins which have been shown to act as endogenous inhibitors of caspases, the enzymatic effectors of apoptosis. XIAP possesses a C-terminal RING...
  • 23-056M - XIAP, active, 250 ug $2,626.50 Add To Cart Qty:
    X-linked inhibitor of apoptosis (XIAP) is one of a group of intracellular proteins which have been shown to act as endogenous inhibitors of caspases, the enzymatic effectors of apoptosis. XIAP possesses a C-terminal RING...
  • 23-057 - Smac/DIABLO, 10 ug $458.35 Add To Cart Qty:
    Smac/DIABLO is a mitochondrial protein that is proteolytically processed and released during apoptosis along with cytochrome c and other pro-apoptotic factors. Once in the cytosol, Smac/DIABLO binds to inhibitors of...
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