- Assay Kits
- Proteins & Enzymes
- Membrane Preps
- Frozen Cells
- Cell Lines
Eurofins is the original provider of purified kinases geared towards screening and profiling potential drugs. Since our early origins at the turn of the century, we have been continuously expanding our portfolio of recombinant proteins.
Our portfolio includes more than 370 active, inactive, and unactivated protein kinases and a large selection of disease-relevant mutants. All of our enzymes are available in multiple pack sizes including 10 μg, 250 μg or bulk (1 mg and greater) to provide you with flexible options from a one-time experiment to a full-blown HTS campaign.
Advantages of our kinase enzymes:
Figure 1. Eurofins purified kinases give superior results compared to other commercial sources.
A) Results from assays using wild-type B-Raf (Cat# 14-530) and the disease relevant mutant B-Raf V600E (Cat# 14-557) compared to another supplier. B) The specific activity of our enzymes, PAK1 (Cat# 14- 927), JAK1 (Cat# 14-918), B-Raf and B-Raf V600E as described in (A) were compared to other suppliers (specific activity was normalized to that of the Eurofins enzymes). Catalytic kinase assays shown in (A) and (B) were run in identical conditions for the given kinase target. Incorporation of radiolabeled phosphate into a peptide substrate was measured after substrate capture on a filter membrane.