CYL3067 - PrecisION™ hKv2.1/hKv9.2- CHO Recombinant Stable Cell Line

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  • Product Description

    Recombinant CHO-K1 cell line co-expressing the human Kv2.1 (voltage-gated potassium channel, Shab-related subfamily, member 1, KCNB1, accession number NM_004975) and the human Kv9.2 (voltage-gated, delayed rectifier potassium channel, accession number NM_020697).

    Additional Resource :  CYL3067100614 Datasheet

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    Contents: 2 x 1 mL aliquots containing 1.41 x 106 cells/mL in 7.5% DMSO at passage 13.
    Storage: Vials are to be stored in liquid N2.
    GMO: This product contains genetically modified organisms.
    Reference 1: 1. Bowden, S., Yeung, S. Y. and Robertson B. (2003). Pharmacology of Voltage Gated K+ Channels. Tocris Reviews.
    Reference 2: 2. Coetzee, W.A., Amarillo. Y., Chiu. J., Chow. A., Lau, D., McCormack, T., Moreno, H., Nadal, M.S., Ozaita, A., Pountney, D., Saganich, M., Vega-Saenz de Miera, E. and Rudy, B. (1999). Molecular diversity of K+ channels. Ann N Y Acad Sci 868, 233-28
    Reference 3: 3. Drewe, J.A., Verma, S., Frech, G. and Joho, R.H. (1992). Distinct spatial and temporal expression patterns of K+ channel mRNAs from different subfamilies. J Neurosci 12, 538-548.
    Reference 4: 4. Gutman, G.A., Chandy, K.G., Grissmer, S., Lazdunski, M., McKinnon, D., Pardo, L.A., Robertson, G.A., Rudy, B., Sanguinetti, M.C., Stuhmer, W. and Wang, X. (2005). International Union of Pharmacology. LIII. Nomenclature and molecular relationships
    Reference 5: 5. Misonou, H., Mohapatra, D.P. and Trimmer, J.S. (2005). Kv2.1: a voltage-gated k+ channel critical to dynamic control of neuronal excitability. Neurotoxicology 26, 743-752.