CYL3065 - PrecisION™ hTRPV3- HEK Recombinant Stable Cell Line

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    Recombinant HEK293 cell line expressing the human TRPV3 ligand-gated ion channel (Transient recetor potential cation channel subfamily V member 3, vanilloid receptor-like 3, accession number AJ487035).

    Additional Resource :  CYL3065100614 Datasheet

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    Contents: 2 x 1 mL aliquots containing 1.10 x 106 cells/mL in 10% DMSO at passage 12.
    Storage: Vials are to be stored in liquid N2.
    GMO: This product contains genetically modified organisms.
    Reference 1: Caterina, M,J,, Schumacher, M.A., Tominaga, M., Rosen, T.A., Levine, J.D. and Julius, D. (1997). The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 389, 816-824
    Reference 2: 2. Chung, M.K., Guler, A.D. and Caterina, M.J. (2005). Biphasic currents evoked by chemical or thermal activation of the heat-gated ion channel, TRPV3. J Biol Chem 280, 15928-15941.
    Reference 3: 3. Chung, M.K., Lee, H., Mizuno, A., Suzuki, M. and Caterina, M.J. (2004a). 2-aminoethoxydiphenyl borate activates and sensitizes the heat-gated ion channel TRPV3. J Neurosci 24, 5177-5182.
    Reference 4: 4. Chung, M.K., Lee, H., Mizuno, A., Suzuki, M. and Caterina, M.J. (2004b). TRPV3 and TRPV4 mediate warmth-evoked currents in primary mouse keratinocytes. J Biol Chem 279, 21569-21575.
    Reference 5: 5. Facer, P., Casula, M.A., Smith, G.D., Benham, C.D., Chessell, I.P., Bountra, C., Sinisi, M., Birch, R. and Anand, P. (2007). Differential expression of the capsaicin receptor TRPV1 and related novel receptors TRPV3, TRPV4 and TRPM8 in normal human