CYL3063 - PrecisION™ hTRPV1-HEK Recombinant Stable Cell Line

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  • Product Description

    Recombinant HEK293 cell line expressing the human TRPV1 ligand-gated ion channel (capsaicin receptor / vanilloid receptor (VR1), accession number AF196175).

    Additional Resource :  CYL3063091714 Datasheet

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    Contents: 1 mL aliquots containing 15 x 106 cells/mL in 10% DMSO at passage 8.
    Storage: Vials are to be stored in liquid N2.
    GMO: This product contains genetically modified organisms.
    Use Restrictions: For Research Use Only- Not for Use in Diagnostic ProceduresNot for Animal or Human Consumption
    Reference 1: 1. Bevan, S., Hothi, S., Hughes, G., James, I. F., Rang, H. P., Shah, K., Walpole, C. S., and Yeats, J. C. (1992) Capsazepine: a competitive antagonist of the sensory neurone excitant capsaicin Br J Pharmacol 107(2), 544-552
    Reference 2: 2. Caterina, M. J., Schumacher, M. A., Tominaga, M., Rosen, T. A., Levine, J. D., and Julius, D. (1997) The capsaicin receptor: a heat-activated ion channel in the pain pathway Nature 389(6653), 816-824
    Reference 3: 3. Clapham, D. E., Runnels, L. W., and Strubing, C. (2001) The TRP ion channel family Nature reviews 2(6), 387-396
    Reference 4: 4. Cui, M., Honore, P., Zhong, C., Gauvin, D., Mikusa, J., Hernandez, G., Chandran, P., Gomtsyan, A., Brown, B., Bayburt, E. K., Marsh, K., Bianchi, B., McDonald, H., Niforatos, W., Neelands, T. R., Moreland, R. B., Decker, M. W., Lee, C. H., Sulliva
    Reference 5: 5. Gunthorpe, M. J., Rami, H. K., Jerman, J. C., Smart, D., Gill, C. H., Soffin, E. M., Luis Hannan, S., Lappin, S. C., Egerton, J., Smith, G. D., Worby, A., Howett, L., Owen, D., Nasir, S., Davies, C. H., Thompson, M., Wyman, P. A., Randall, A. D.,