CYL3027 - PrecisION™ hKv4.3/hKChIP1-CHO Recombinant Stable Cell Line

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  • Product Description

    Recombinant CHO-K1 cell line co-expressing the human Kv4.3 (voltage-gated potassium channel, accession number NM_004980) and the human Kv channel interacting protein KChIP1 (accession number NM_14592).

    Additional Resource :  CYL3027091114 Datasheet

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    Contents: 2 x 1 mL aliquots containing 1.04 x 106 cells/mL in 10% DMSO at passage 8.
    Storage: Vials are to be stored in liquid N2.
    GMO: This product contains genetically modified organisms.
    Reference 1: 1. An, W.F., Bowlby, M.R., Betty, M., Cao, J., Ling, H.P., Mendoza, G., Hinson, J.W., Mattsson, K.I., Strassle, B.W., Trimmer, J.S. and Rhodes, K.J. (2000). Modulation of A-type potassium channels by a family of calcium sensors. Nature 403, 553-556.
    Reference 2: 2. Beck, E.J., Bowlby, M., An, W.F., Rhodes, K.J. and Covarrubias, M. (2002). Remodelling inactivation gating of Kv4 channels by KChIP1, a small-molecular-weight calcium-binding protein. J Physiol 538, 691-706.
    Reference 3: 3. Gutman, G.A., Chandy, K.G., Grissmer, S., Lazdunski, M., McKinnon, D, Pardo, L.A., Robertson, G.A., Rudy, B., Sanguinetti, M.C., Stuhmer, W, and Wang, X. (2005). International Union of Pharmacology. LIII. Nomenclature and molecular relationships o
    Reference 4: 4. Hoffman, D.A., Magee, J.C., Colbert, C.M. and Johnston, D. (1997). K+ channel regulation of signal propagation in dendrites of hippocampal pyramidal neurons. Nature 387, 869-875.
    Reference 5: 5. Holmqvis, M.H., Cao, J., Hernandez-Pineda, R., Jacobson, M.D., Carroll, K.I., Sung, M.A., Betty, M., Ge, P., Gilbride, K.J., Brown, M.E., Jurman, M.E., Lawson, D., Silos-Santiago, I., Xie, Y., Covarrubias, M., Rhodes, K.J., Distefano, P.S. and An,
    Reference 6: 6. Nerbonne, J.M.. (2000). Molecular basis of functional voltage-gated K+ channel diversity in the mammalian myocardium. J Physiol (Lond) 525, 285-298.