CYL3022 - PrecisION™ hKv2.1-CHO Recombinant Stable Cell Line

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  • Product Description

    Recombinant CHO-K1 cell line expressing the human voltage-gated potassium channel Kv2.1 (accession number NM_004975).

    Additional Resource :  CYL3022091114 Datasheet

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    Contents: 2 x 1 mL aliquots containing 1.56 x 106 cells/mL in 7.5% DMSO at passage 12.
    Storage: Vials are to be stored in liquid N2.
    GMO: This product contains genetically modified organisms.
    Reference 1: 1. Albrecht, B., Lorra, C., Stocker, M. and Pongs, O. (1993) Cloning and characterization of a human delayed rectifier potassium channel gene. Receptors Channels. 1: 99-110.
    Reference 2: 2. Coetzee, W.A., Amarillo, Y., Chiu, J., Chow, A., Lau, D., McCormack, T., Moreno, H., Nadal, M.S., Ozaita, A., Pountney, D., Saganich, M., Vega-Saenz de Miera, E. and Rudy B. (1999) Molecular diversity of K+ channels. Ann N Y Acad Sci. 868: 233-285
    Reference 3: 3. Drewe, J.A., Verma, S., Frech, G. and Joho, R.H. (1992) Distinct spatial and temporal expression patterns of K+ channel mRNAs from different subfamilies. J Neurosci. 12: 538-548.
    Reference 4: 4. Gutman, G.A., Chandy, K.G., Grissmer, S., Lazdunski, M., McKinnon, D., Pardo, L.A., Robertson, G.A., Rudy, B., Sanguinetti, M.C., Stuhmer, W. and Wang, X. (2005) International Union of Pharmacology. LIII. Nomenclature and molecular relationships o
    Reference 5: 5. Misonou, H., Mohapatra, D.P. and Trimmer, J.S. (2005) Kv2.1: a voltage-gated k+ channel critical to dynamic control of neuronal excitability. Neurotoxicology. 26: 743-752.
    Reference 6: 6. Murakoshi, H., Shi G., Scannevin, R.H. and Trimmer, J.S. (1997) Phosphorylation of the Kv2.1 K+ channel alters voltage-dependent activation. Mol Pharmacol. 52: 821-828.