CYL3021 - PrecisION™ hKv1.8-CHO Recombinant Stable Cell Line

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  • Product Description

    Recombinant CHO-K1 cell line expressing the human voltage-gated potassium channel Kv1.8.

    Additional Resource :  CYL3021091014 Datasheet

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    Contents: 2 x 1 mL aliquots containing 1.02 x 106 cells/mL in 10% DMSO at passage 11.
    Storage: Vials are to be stored in liquid N2.
    GMO: This product contains genetically modified organisms.
    Reference 1: 1. Gutman, G.A., Chandy, K.G., Grissmer, S., Lazdunski, M., McKinnon, D., Pardo, L.A., Robertson, G.A., Rudy, B., Sanguinetti, M.C., Stuhmer, W. and Wang, X. (2005). International Union of Pharmacology. LIII. Nomenclature and molecular relationships
    Reference 2: 2. Lang, R., Lee, G., Liu, W., Tian, S., Rafi, H., Orias, M., Segal, A.S. and Desir, G.V. (2000). KCNA10: a novel ion channel functionally related to both voltage-gated potassium and CNG cation channels. Am J Physiol Renal Physiol 278: F1013-1021.
    Reference 3: 3. Schroeder, K., Neagle, B., Trezise D.J. and Worley, J. (2003) IonWorksTM HT: a new high-throughput electrophysiology measurement platform. J. Biomol Screen 8 (1): 50-64.
    Reference 4: 4. Yao, X., Liu, Y., Tung, F. and Desir, G.V. (1996). Genomic structure and regulation of Kcn1, a cGMP-gated potassium channel. Am J Physiol 271: F37-41.
    Reference 5: 5. Yao, X., Segal, A.S., Welling, P., Zhang, X., McNicholas, C.M., Engel, D., Boulpaep, E.L. and Desir, G.V. (1995). Primary structure and functional expression of a cGMP-gated potassium channel. Proc Natl Acad Sci U S A 92: 11711-11715.