CYL3018 - PrecisION™ hKv1.5-CHO Recombinant Stable Cell Line

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  • Product Description

    Recombinant CHO-K1 cell line expressing the human Kv1.5 potassium channel (accession number NM_002234).

    Additional Resource :  CYL3018091014 Datasheet

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    Contents: 2 x 1 mL aliquots containing 2.08 x 106 cells/mL in 7.5% DMSO at passage 10.
    Storage: Vials are to be stored in liquid N2.
    GMO: This product contains genetically modified organisms.
    Reference 1: 1. Bowden, S. ,Yeung, S. and Robertson, B. (2003). Pharmacology of voltage-gated K+ channels. Tocris Reviews No. 22: 1-11.
    Reference 2: 2. Chen, F.S.P. and Fedida, D (1998). On the mechanism by which 4-AP occludes Quinidine block of the cardiac K channel, hKv1.5. Journal of General Physiology 111: 539-554.
    Reference 3: 3. Grissmer, S., Nguyen, A.N., Aiyar, J., Hanson, D.C., Mather, R.J., Gutman, G.A., Karmilowicz, M.J., Auperin, D.D. and Chandy, K.G. (1994). Pharmacological characterisation of five cloned voltage-gated K channels, Types Kv1.1, 1.2, 1.3, 1.5 and 3.1
    Reference 4: 4. Lacerda, A.E., Roy, M-L., Lewis, E.W. and Rampe, D. (1997). Interactions of non-sedating antihistamine Loratadine with Kv1.5-type potassium channel cloned from human heart. Molecular Pharmacology 52: 314-322.
    Reference 5: 5. Snyders, D.J., Tamkun, M.M. and Bennett, P.B. (1993). A rapidly activating and slowly inactivating potassium channel cloned from human heart: Functional analysis after stable mammalian cell culture expression. Journal of General Physiology 101: 51