Biological Information

Family:

Kinase

Sub Family:

TKL

Class:

Protein Serine/Threonine

Protein Name:

TAK1

Uniprot Number:

O43318

Protein Aliases:

TGF-beta activated kinase 1

Gene Name:

MAP3K7

Gene ID:

6885

Gene Aliases:

MEKK7|TAK1

Accession Number:

NM_003188

Organism:

Human

Assay Information

Assay Type:

Biochemical

Assay Sub Type:

Enzymatic

Functional Mode:

Antagonist

Measured Response:

Scintillation

Testing Information

Tracer:

33P

ATP Concentration:

45 µM

Incubation:

40 min at RT

Test Sample Requirements:

Minimum for 1) Screen: 60 µl of 10 mM stock -OR- 1 mg (pre-weighed) for 10µM final testing. 2) Dose Response: 90 µl of 10 mM stock -OR- 1 mg (pre-weighed) for a top concentration at 10 µM.

Minimum Order Quantity:

10

Turnaround Time

Standard:

15 Business Days

Reference Compound Data

PubChem ID

122130844

Name

Staurosporine

Measurement

126nM - IC50

Clinical Relevance

Therapeutic Area:

Oncology/Immuno-Oncology

Additional Information

Brand:

LeadHunter

Testing Location:

France - Celle L'Evescault