Biological Information

Family:

GPCR

Sub Family:

Somatostatin

Class:

Class A

Accession Number:

NM_001049

Organism:

Mouse

Assay Information

Assay Type:

Biochemical

Assay Sub Type:

Binding

Detection Method:

Radiometric

Measured Response:

Scintillation

Testing Information

Ligand:

[125I]Tyr11-somatostatin-14

Ligand Kd (nM):

0.08

Ligand Concentration:

0.05 nM

Non Specific:

300 nM Somatostatin-14

Incubation:

60 min at 37°C

Control Inhibitor:

Somatostatin-14

Test Concentration / Dose:

Eurofins will provide IC/EC50 calculation if 5 or more concentrations are selected.

Test Sample Requirements:

Minimum for 1) Screen: 60 µl of 10 mM stock -OR- 1 mg (pre-weighed) for 10µM final testing. 2) Dose Response: 90 µl of 10 mM stock -OR- 1 mg (pre-weighed) for a top concentration at 10 µM.

Minimum Order Quantity:

2

Turnaround Time

Standard:

10 Business Days

Reference Compound Data

PubChem ID

16133799

Name

BIM 23056

Measurement

1200nM - IC50

PubChem ID

44291156

Name

Somatostatin-14

Measurement

0.2nM - IC50

PubChem ID

Name

[D-Trp8]somatostatin

Measurement

0.09nM - IC50

PubChem ID

Name

somatostatine-28

Measurement

0.1nM - IC50

Clinical Relevance

Therapeutic Area:

Metabolic Diseases

Additional Information

Brand:

LeadHunter

Testing Location:

France - Celle L'Evescault

RELATED SOLUTIONS

Item: P1
Item: P3