Biological Information

Family:

GPCR

Sub Family:

Neuropeptide Y

Class:

Class A

Accession Number:

XM_005263031

Organism:

Rat

Tissue:

Brain

Assay Information

Assay Type:

Biochemical

Assay Sub Type:

Binding

Detection Method:

Radiometric

Measured Response:

Scintillation

Testing Information

Ligand:

[125I]peptide YY

Ligand Kd (nM):

0.1

Ligand Concentration:

0.05 nM

Non Specific:

1 µM NPY

Incubation:

120 min at RT

Control Inhibitor:

NPY

Test Concentration / Dose:

Eurofins will provide IC/EC50 calculation if 5 or more concentrations are selected.

Test Sample Requirements:

Minimum for 1) Screen: 60 µl of 10 mM stock -OR- 1 mg (pre-weighed) for 10µM final testing. 2) Dose Response: 90 µl of 10 mM stock -OR- 1 mg (pre-weighed) for a top concentration at 10 µM.

Minimum Order Quantity:

2

Turnaround Time

Standard:

15 Business Days

Reference Compound Data

PubChem ID

Name

NPY

Measurement

0.46nM - IC50

PubChem ID

Name

NPY-(13-36)

Measurement

23nM - IC50

PubChem ID

Name

[Leu31,Pro34]NPY

Measurement

1.2nM - IC50

Clinical Relevance

Therapeutic Area:

Metabolic Diseases

Additional Information

Brand:

LeadHunter

Testing Location:

France - Celle L'Evescault

RELATED SOLUTIONS

Item: P9