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Example Input Mode:
Partner Data
CBIS
Matrix
Example Data Type:
Secondary Screen (Kd)
Primary Screen(% control or competition)
If the input file contains Primary and Secondary Data, use:
Primary
Secondary
Assay Data File:
.txt or .csv format - download examples:
Bromodomain
Kd
Primary
To highlight spots, select a compound(s), click 'fill' and select entries.
Create Images for:
MLN-120B
Highlight These Spots (
fill
):
MLN-120B|CLK1|640
MLN-120B|CLK2|2300
MLN-120B|CLK4|1000
MLN-120B|DYRK1A|2100
MLN-120B|IKK-alpha|1000
MLN-120B|IKK-beta|19
MLN-120B|PIK4CB|270
MLN-120B|TYK2(JH2domain-pseudokinase)|500
MLN-120B|CLK1
MLN-120B|CLK2
MLN-120B|CLK4
MLN-120B|DYRK1A
MLN-120B|IKK-alpha
MLN-120B|IKK-beta
MLN-120B|PIK4CB
MLN-120B|TYK2(JH2domain-pseudokinase)
MLN-120B|CLK1|640
MLN-120B|CLK2|2300
MLN-120B|CLK4|1000
MLN-120B|DYRK1A|2100
MLN-120B|IKK-alpha|1000
MLN-120B|IKK-beta|19
MLN-120B|PIK4CB|270
MLN-120B|TYK2(JH2domain-pseudokinase)|500
clear
Select Highlight spots color from Pallette:
(also used in table view)
Tree Image Options
Restore default options
Spot options:
IndianRed
PaleGreen
Gold
PowderBlue
Fill?
Outline?
Outline thickness:
1
2
3
4
5
Select Spots Color from Pallette:
(spot highlight color below)
micro
nano
Spot Size:
Scaling Factor:
.1
.2
.3
.4
.5
.6
.7
.8
.9
1
1.1
1.2
1.3
Area increase factor:
100%
90%
80%
70%
60%
50%
(per change of 10x Kd or 10% Competition)
Legend options:
Left align Text
Right align Text
Label options:
Compound Name?
Compound Name Font:
.5
1
1.5
2
Show Assay Panel information?
Show Panel Spots?
Append Concentration? (i.e., 'AB500@1000nm'; check before loading.)
Background Image:
Target labels?
Dark Tree Branch image?
Hide Lipid, Mutant, ATypical and Pathogen?
Spot options:
Spot Color transparency level:
none
low
medium-low
medium
high
no color
Spot Cutoff Value:
Kd (nM) (Blank for no cutoff)
Spot outline only?
Format:
JPEG(200KB per image)
Publication Quality(5MB image)
Create Publication Quality (5MB bitmap) Image for:
Select Compound
MLN-120B
size/quality
100
90
80
70
60
50
40
30
% of original
White Space Border:
Yes
No
Preview and Highlighting
Highlight an assay by clicking on the spot or checking the box next to the Gene Symbol Name.
Click 'Update' to create the new images.
Compound To Highlight:
None
MLN-120B
Highlight Panel?
* WildType kinase assays appear in both the main TREEspot and Mutant kinase dendrogams.
Human Kinome image created by KINOMEscan.
2 images created. To download (copy and paste) all images to your local machine click Open/Browse Image Folder.
Images Saved To:
D:\Eurofins\PROD\Applications\FrontOffice_Discovery\StudyManagement\TreeSpot\HTSTools\TreeImages\323_uyjabmcw5ebcqk3of1gwnaxc\
Open/Browse Image Folder
View Options:
(These options do not modify the images that have been created, only the view on this page)
MLN-120B
Legend
Show Selected
Size:
Select Size
small
medium
full size
Images per Row:
1
Legend Resize?
Hover the cursor to identify spots and click to highlighted it. To save an image click the Zoom/Download link.
Zoom/Download
Highlight
Locate an Assay
CLK1
CLK2
CLK4
DYRK1A
IKK-alpha
IKK-beta
PIK4CB
TYK2(JH2domain-pseudokinase)
Legend
Data Table View:
Show All Data
Only Selected Compounds/Trees
TREE
spot
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