Reset
Start Over
Help
Publication Permission Requests
Example Input Mode:
Partner Data
CBIS
Matrix
Example Data Type:
Secondary Screen (Kd)
Primary Screen(% control or competition)
If the input file contains Primary and Secondary Data, use:
Primary
Secondary
Assay Data File:
.txt or .csv format - download examples:
Bromodomain
Kd
Primary
To highlight spots, select a compound(s), click 'fill' and select entries.
Create Images for:
LY-333531
Highlight These Spots (
fill
):
LY-333531|AAK1|900
LY-333531|AKT2|8700
LY-333531|AKT3|1400
LY-333531|ARK5|1800
LY-333531|BIKE|430
LY-333531|CAMK1D|4500
LY-333531|CAMK2A|4500
LY-333531|CAMK2D|4600
LY-333531|CAMK2G|7800
LY-333531|CAMKK1|5000
LY-333531|CAMKK2|2400
LY-333531|CDK4-cyclinD1|280
LY-333531|CDK7|1700
LY-333531|CDKL5|4100
LY-333531|CHEK1|540
LY-333531|CHEK2|3700
LY-333531|CIT|1400
LY-333531|CLK1|910
LY-333531|CLK2|420
LY-333531|CLK4|1900
LY-333531|CSNK2A2|6700
LY-333531|DAPK1|970
LY-333531|DAPK3|8000
LY-333531|DMPK|280
LY-333531|DYRK1A|250
LY-333531|DYRK1B|5400
LY-333531|ERK8|88
LY-333531|FLT3|1900
LY-333531|GAK|1100
LY-333531|GRK1|800
LY-333531|GRK4|590
LY-333531|GRK7|310
LY-333531|GSK3B|2600
LY-333531|HIPK1|230
LY-333531|HIPK2|140
LY-333531|HIPK3|77
LY-333531|HPK1|2600
LY-333531|ICK|240
LY-333531|JAK3(JH1domain-catalytic)|1200
LY-333531|LATS1|2600
LY-333531|LATS2|640
LY-333531|LKB1|5900
LY-333531|LOK|280
LY-333531|MAP3K2|710
LY-333531|MAP3K3|170
LY-333531|MAP4K2|290
LY-333531|MAP4K3|8400
LY-333531|MEK4|930
LY-333531|MEK5|1100
LY-333531|MEK6|3900
LY-333531|MINK|310
LY-333531|MKNK1|7100
LY-333531|MLK1|1400
LY-333531|MST2|960
LY-333531|MYLK|290
LY-333531|PCTK1|2600
LY-333531|PDPK1|700
LY-333531|PHKG1|3700
LY-333531|PIM1|270
LY-333531|PIM2|1700
LY-333531|PIM3|12
LY-333531|PIP5K1A|690
LY-333531|PIP5K1C|510
LY-333531|PIP5K2B|830
LY-333531|PKAC-alpha|5400
LY-333531|PKAC-beta|3200
LY-333531|PKN1|350
LY-333531|PKN2|1500
LY-333531|PLK4|4700
LY-333531|PRKCD|3.6
LY-333531|PRKCE|11
LY-333531|PRKCH|1800
LY-333531|PRKCI|1400
LY-333531|PRKCQ|2.5
LY-333531|PRKD2|890
LY-333531|PRKG2|3100
LY-333531|PRP4|1600
LY-333531|RIOK1|810
LY-333531|RIOK3|650
LY-333531|ROS1|5800
LY-333531|RPS6KA4(Kin.Dom.1-N-terminal)|6100
LY-333531|RPS6KA5(Kin.Dom.1-N-terminal)|1300
LY-333531|RSK1(Kin.Dom.1-N-terminal)|400
LY-333531|RSK2(Kin.Dom.1-N-terminal)|3600
LY-333531|RSK3(Kin.Dom.1-N-terminal)|280
LY-333531|RSK4(Kin.Dom.1-N-terminal)|2300
LY-333531|S6K1|210
LY-333531|SGK3|1400
LY-333531|SLK|400
LY-333531|SNARK|320
LY-333531|SRPK1|1200
LY-333531|SRPK2|1100
LY-333531|SRPK3|1600
LY-333531|STK33|2600
LY-333531|TAOK1|1800
LY-333531|TAOK2|3900
LY-333531|TAOK3|97
LY-333531|TBK1|970
LY-333531|TLK1|2100
LY-333531|YSK4|48
LY-333531|AAK1
LY-333531|AKT2
LY-333531|AKT3
LY-333531|ARK5
LY-333531|BIKE
LY-333531|CAMK1D
LY-333531|CAMK2A
LY-333531|CAMK2D
LY-333531|CAMK2G
LY-333531|CAMKK1
LY-333531|CAMKK2
LY-333531|CDK4-cyclinD1
LY-333531|CDK7
LY-333531|CDKL5
LY-333531|CHEK1
LY-333531|CHEK2
LY-333531|CIT
LY-333531|CLK1
LY-333531|CLK2
LY-333531|CLK4
LY-333531|CSNK2A2
LY-333531|DAPK1
LY-333531|DAPK3
LY-333531|DMPK
LY-333531|DYRK1A
LY-333531|DYRK1B
LY-333531|ERK8
LY-333531|FLT3
LY-333531|GAK
LY-333531|GRK1
LY-333531|GRK4
LY-333531|GRK7
LY-333531|GSK3B
LY-333531|HIPK1
LY-333531|HIPK2
LY-333531|HIPK3
LY-333531|HPK1
LY-333531|ICK
LY-333531|JAK3(JH1domain-catalytic)
LY-333531|LATS1
LY-333531|LATS2
LY-333531|LKB1
LY-333531|LOK
LY-333531|MAP3K2
LY-333531|MAP3K3
LY-333531|MAP4K2
LY-333531|MAP4K3
LY-333531|MEK4
LY-333531|MEK5
LY-333531|MEK6
LY-333531|MINK
LY-333531|MKNK1
LY-333531|MLK1
LY-333531|MST2
LY-333531|MYLK
LY-333531|PCTK1
LY-333531|PDPK1
LY-333531|PHKG1
LY-333531|PIM1
LY-333531|PIM2
LY-333531|PIM3
LY-333531|PIP5K1A
LY-333531|PIP5K1C
LY-333531|PIP5K2B
LY-333531|PKAC-alpha
LY-333531|PKAC-beta
LY-333531|PKN1
LY-333531|PKN2
LY-333531|PLK4
LY-333531|PRKCD
LY-333531|PRKCE
LY-333531|PRKCH
LY-333531|PRKCI
LY-333531|PRKCQ
LY-333531|PRKD2
LY-333531|PRKG2
LY-333531|PRP4
LY-333531|RIOK1
LY-333531|RIOK3
LY-333531|ROS1
LY-333531|RPS6KA4(Kin.Dom.1-N-terminal)
LY-333531|RPS6KA5(Kin.Dom.1-N-terminal)
LY-333531|RSK1(Kin.Dom.1-N-terminal)
LY-333531|RSK2(Kin.Dom.1-N-terminal)
LY-333531|RSK3(Kin.Dom.1-N-terminal)
LY-333531|RSK4(Kin.Dom.1-N-terminal)
LY-333531|S6K1
LY-333531|SGK3
LY-333531|SLK
LY-333531|SNARK
LY-333531|SRPK1
LY-333531|SRPK2
LY-333531|SRPK3
LY-333531|STK33
LY-333531|TAOK1
LY-333531|TAOK2
LY-333531|TAOK3
LY-333531|TBK1
LY-333531|TLK1
LY-333531|YSK4
LY-333531|AAK1|900
LY-333531|AKT2|8700
LY-333531|AKT3|1400
LY-333531|ARK5|1800
LY-333531|BIKE|430
LY-333531|CAMK1D|4500
LY-333531|CAMK2A|4500
LY-333531|CAMK2D|4600
LY-333531|CAMK2G|7800
LY-333531|CAMKK1|5000
LY-333531|CAMKK2|2400
LY-333531|CDK4-cyclinD1|280
LY-333531|CDK7|1700
LY-333531|CDKL5|4100
LY-333531|CHEK1|540
LY-333531|CHEK2|3700
LY-333531|CIT|1400
LY-333531|CLK1|910
LY-333531|CLK2|420
LY-333531|CLK4|1900
LY-333531|CSNK2A2|6700
LY-333531|DAPK1|970
LY-333531|DAPK3|8000
LY-333531|DMPK|280
LY-333531|DYRK1A|250
LY-333531|DYRK1B|5400
LY-333531|ERK8|88
LY-333531|FLT3|1900
LY-333531|GAK|1100
LY-333531|GRK1|800
LY-333531|GRK4|590
LY-333531|GRK7|310
LY-333531|GSK3B|2600
LY-333531|HIPK1|230
LY-333531|HIPK2|140
LY-333531|HIPK3|77
LY-333531|HPK1|2600
LY-333531|ICK|240
LY-333531|JAK3(JH1domain-catalytic)|1200
LY-333531|LATS1|2600
LY-333531|LATS2|640
LY-333531|LKB1|5900
LY-333531|LOK|280
LY-333531|MAP3K2|710
LY-333531|MAP3K3|170
LY-333531|MAP4K2|290
LY-333531|MAP4K3|8400
LY-333531|MEK4|930
LY-333531|MEK5|1100
LY-333531|MEK6|3900
LY-333531|MINK|310
LY-333531|MKNK1|7100
LY-333531|MLK1|1400
LY-333531|MST2|960
LY-333531|MYLK|290
LY-333531|PCTK1|2600
LY-333531|PDPK1|700
LY-333531|PHKG1|3700
LY-333531|PIM1|270
LY-333531|PIM2|1700
LY-333531|PIM3|12
LY-333531|PIP5K1A|690
LY-333531|PIP5K1C|510
LY-333531|PIP5K2B|830
LY-333531|PKAC-alpha|5400
LY-333531|PKAC-beta|3200
LY-333531|PKN1|350
LY-333531|PKN2|1500
LY-333531|PLK4|4700
LY-333531|PRKCD|3.6
LY-333531|PRKCE|11
LY-333531|PRKCH|1800
LY-333531|PRKCI|1400
LY-333531|PRKCQ|2.5
LY-333531|PRKD2|890
LY-333531|PRKG2|3100
LY-333531|PRP4|1600
LY-333531|RIOK1|810
LY-333531|RIOK3|650
LY-333531|ROS1|5800
LY-333531|RPS6KA4(Kin.Dom.1-N-terminal)|6100
LY-333531|RPS6KA5(Kin.Dom.1-N-terminal)|1300
LY-333531|RSK1(Kin.Dom.1-N-terminal)|400
LY-333531|RSK2(Kin.Dom.1-N-terminal)|3600
LY-333531|RSK3(Kin.Dom.1-N-terminal)|280
LY-333531|RSK4(Kin.Dom.1-N-terminal)|2300
LY-333531|S6K1|210
LY-333531|SGK3|1400
LY-333531|SLK|400
LY-333531|SNARK|320
LY-333531|SRPK1|1200
LY-333531|SRPK2|1100
LY-333531|SRPK3|1600
LY-333531|STK33|2600
LY-333531|TAOK1|1800
LY-333531|TAOK2|3900
LY-333531|TAOK3|97
LY-333531|TBK1|970
LY-333531|TLK1|2100
LY-333531|YSK4|48
clear
Select Highlight spots color from Pallette:
(also used in table view)
Tree Image Options
Restore default options
Spot options:
IndianRed
PaleGreen
Gold
PowderBlue
Fill?
Outline?
Outline thickness:
1
2
3
4
5
Select Spots Color from Pallette:
(spot highlight color below)
micro
nano
Spot Size:
Scaling Factor:
.1
.2
.3
.4
.5
.6
.7
.8
.9
1
1.1
1.2
1.3
Area increase factor:
100%
90%
80%
70%
60%
50%
(per change of 10x Kd or 10% Competition)
Legend options:
Left align Text
Right align Text
Label options:
Compound Name?
Compound Name Font:
.5
1
1.5
2
Show Assay Panel information?
Show Panel Spots?
Append Concentration? (i.e., 'AB500@1000nm'; check before loading.)
Background Image:
Target labels?
Dark Tree Branch image?
Hide Lipid, Mutant, ATypical and Pathogen?
Spot options:
Spot Color transparency level:
none
low
medium-low
medium
high
no color
Spot Cutoff Value:
Kd (nM) (Blank for no cutoff)
Spot outline only?
Format:
JPEG(200KB per image)
Publication Quality(5MB image)
Create Publication Quality (5MB bitmap) Image for:
Select Compound
LY-333531
size/quality
100
90
80
70
60
50
40
30
% of original
White Space Border:
Yes
No
Preview and Highlighting
Highlight an assay by clicking on the spot or checking the box next to the Gene Symbol Name.
Click 'Update' to create the new images.
Compound To Highlight:
None
LY-333531
Highlight Panel?
* WildType kinase assays appear in both the main TREEspot and Mutant kinase dendrogams.
Human Kinome image created by KINOMEscan.
2 images created. To download (copy and paste) all images to your local machine click Open/Browse Image Folder.
Images Saved To:
D:\Eurofins\PROD\Applications\FrontOffice_Discovery\StudyManagement\TreeSpot\HTSTools\TreeImages\244_gmmzddion0vdzurglm0guzfm\
Open/Browse Image Folder
View Options:
(These options do not modify the images that have been created, only the view on this page)
LY-333531
Legend
Show Selected
Size:
Select Size
small
medium
full size
Images per Row:
1
Legend Resize?
Hover the cursor to identify spots and click to highlighted it. To save an image click the Zoom/Download link.
Zoom/Download
Highlight
Locate an Assay
AAK1
AKT3
ARK5
BIKE
CAMKK2
CDK4-cyclinD1
CDK7
CHEK1
CIT
CLK1
CLK2
CLK4
DAPK1
DMPK
DYRK1A
ERK8
FLT3
FLT3
GAK
GRK1
GRK4
GRK7
GSK3B
HIPK1
HIPK2
HIPK3
HPK1
ICK
JAK3(JH1domain-catalytic)
LATS1
LATS2
LOK
MAP3K2
MAP3K3
MAP4K2
MEK4
MEK5
MINK
MLK1
MST2
MYLK
PCTK1
PDPK1
PIM1
PIM2
PIM3
PIP5K1A
PIP5K1C
PIP5K2B
PKN1
PKN2
PRKCD
PRKCE
PRKCH
PRKCI
PRKCQ
PRKD2
PRP4
RIOK1
RIOK3
RPS6KA5(Kin.Dom.1-N-terminal)
RSK1(Kin.Dom.1-N-terminal)
RSK3(Kin.Dom.1-N-terminal)
RSK4(Kin.Dom.1-N-terminal)
S6K1
SGK3
SLK
SNARK
SRPK1
SRPK2
SRPK3
STK33
TAOK1
TAOK3
TBK1
TLK1
YSK4
Legend
Data Table View:
Show All Data
Only Selected Compounds/Trees
TREE
spot
Copyright © 2005-2012 KINOMEscan, a division of DiscoveRx Corp. All Rights Reserved.