Reset
Start Over
Help
Publication Permission Requests
Example Input Mode:
Partner Data
CBIS
Matrix
Example Data Type:
Secondary Screen (Kd)
Primary Screen(% control or competition)
If the input file contains Primary and Secondary Data, use:
Primary
Secondary
Assay Data File:
.txt or .csv format - download examples:
Bromodomain
Kd
Primary
To highlight spots, select a compound(s), click 'fill' and select entries.
Create Images for:
LY-317615
Highlight These Spots (
fill
):
LY-317615|AAK1|2700
LY-317615|AKT3|1000
LY-317615|AMPK-alpha2|5000
LY-317615|AXL|3300
LY-317615|BIKE|2900
LY-317615|CAMK2D|2800
LY-317615|CAMKK2|6700
LY-317615|CDK2|5000
LY-317615|CDK3|1100
LY-317615|CDK7|2600
LY-317615|CDK9|1300
LY-317615|CDKL2|3400
LY-317615|CLK1|510
LY-317615|CLK2|430
LY-317615|CLK4|1600
LY-317615|DMPK|2200
LY-317615|DRAK1|760
LY-317615|DYRK1A|160
LY-317615|DYRK1B|1000
LY-317615|ERK8|76
LY-317615|FGFR1|4000
LY-317615|FLT3|330
LY-317615|FLT4|3800
LY-317615|GRK1|1700
LY-317615|GRK7|1300
LY-317615|GSK3B|8.3
LY-317615|HIPK1|1000
LY-317615|HIPK2|720
LY-317615|HIPK4|1200
LY-317615|HPK1|1800
LY-317615|ICK|680
LY-317615|JAK3(JH1domain-catalytic)|1700
LY-317615|MELK|5600
LY-317615|MET|2800
LY-317615|MINK|3500
LY-317615|MST2|1900
LY-317615|MST4|6900
LY-317615|MYLK4|230
LY-317615|PAK3|4300
LY-317615|PCTK1|5300
LY-317615|PDGFRB|3300
LY-317615|PFTAIRE2|4900
LY-317615|PFTK1|1500
LY-317615|PHKG1|4200
LY-317615|PIM1|200
LY-317615|PIM2|870
LY-317615|PIM3|1100
LY-317615|PIP5K1C|6600
LY-317615|PKAC-alpha|330
LY-317615|PKAC-beta|590
LY-317615|PKN1|5100
LY-317615|PRKCD|25
LY-317615|PRKCE|8.9
LY-317615|PRKCH|46
LY-317615|PRKCQ|36
LY-317615|PRKG1|1100
LY-317615|PRKG2|170
LY-317615|RPS6KA4(Kin.Dom.1-N-terminal)|2500
LY-317615|RPS6KA5(Kin.Dom.1-N-terminal)|370
LY-317615|RSK1(Kin.Dom.1-N-terminal)|1600
LY-317615|RSK2(Kin.Dom.1-N-terminal)|87
LY-317615|RSK3(Kin.Dom.1-N-terminal)|220
LY-317615|RSK4(Kin.Dom.1-N-terminal)|25
LY-317615|S6K1|1800
LY-317615|SLK|3100
LY-317615|SNARK|4100
LY-317615|STK16|2500
LY-317615|STK33|4900
LY-317615|TLK1|510
LY-317615|TLK2|1400
LY-317615|TNK1|3400
LY-317615|YSK4|1600
LY-317615|AAK1
LY-317615|AKT3
LY-317615|AMPK-alpha2
LY-317615|AXL
LY-317615|BIKE
LY-317615|CAMK2D
LY-317615|CAMKK2
LY-317615|CDK2
LY-317615|CDK3
LY-317615|CDK7
LY-317615|CDK9
LY-317615|CDKL2
LY-317615|CLK1
LY-317615|CLK2
LY-317615|CLK4
LY-317615|DMPK
LY-317615|DRAK1
LY-317615|DYRK1A
LY-317615|DYRK1B
LY-317615|ERK8
LY-317615|FGFR1
LY-317615|FLT3
LY-317615|FLT4
LY-317615|GRK1
LY-317615|GRK7
LY-317615|GSK3B
LY-317615|HIPK1
LY-317615|HIPK2
LY-317615|HIPK4
LY-317615|HPK1
LY-317615|ICK
LY-317615|JAK3(JH1domain-catalytic)
LY-317615|MELK
LY-317615|MET
LY-317615|MINK
LY-317615|MST2
LY-317615|MST4
LY-317615|MYLK4
LY-317615|PAK3
LY-317615|PCTK1
LY-317615|PDGFRB
LY-317615|PFTAIRE2
LY-317615|PFTK1
LY-317615|PHKG1
LY-317615|PIM1
LY-317615|PIM2
LY-317615|PIM3
LY-317615|PIP5K1C
LY-317615|PKAC-alpha
LY-317615|PKAC-beta
LY-317615|PKN1
LY-317615|PRKCD
LY-317615|PRKCE
LY-317615|PRKCH
LY-317615|PRKCQ
LY-317615|PRKG1
LY-317615|PRKG2
LY-317615|RPS6KA4(Kin.Dom.1-N-terminal)
LY-317615|RPS6KA5(Kin.Dom.1-N-terminal)
LY-317615|RSK1(Kin.Dom.1-N-terminal)
LY-317615|RSK2(Kin.Dom.1-N-terminal)
LY-317615|RSK3(Kin.Dom.1-N-terminal)
LY-317615|RSK4(Kin.Dom.1-N-terminal)
LY-317615|S6K1
LY-317615|SLK
LY-317615|SNARK
LY-317615|STK16
LY-317615|STK33
LY-317615|TLK1
LY-317615|TLK2
LY-317615|TNK1
LY-317615|YSK4
LY-317615|AAK1|2700
LY-317615|AKT3|1000
LY-317615|AMPK-alpha2|5000
LY-317615|AXL|3300
LY-317615|BIKE|2900
LY-317615|CAMK2D|2800
LY-317615|CAMKK2|6700
LY-317615|CDK2|5000
LY-317615|CDK3|1100
LY-317615|CDK7|2600
LY-317615|CDK9|1300
LY-317615|CDKL2|3400
LY-317615|CLK1|510
LY-317615|CLK2|430
LY-317615|CLK4|1600
LY-317615|DMPK|2200
LY-317615|DRAK1|760
LY-317615|DYRK1A|160
LY-317615|DYRK1B|1000
LY-317615|ERK8|76
LY-317615|FGFR1|4000
LY-317615|FLT3|330
LY-317615|FLT4|3800
LY-317615|GRK1|1700
LY-317615|GRK7|1300
LY-317615|GSK3B|8.3
LY-317615|HIPK1|1000
LY-317615|HIPK2|720
LY-317615|HIPK4|1200
LY-317615|HPK1|1800
LY-317615|ICK|680
LY-317615|JAK3(JH1domain-catalytic)|1700
LY-317615|MELK|5600
LY-317615|MET|2800
LY-317615|MINK|3500
LY-317615|MST2|1900
LY-317615|MST4|6900
LY-317615|MYLK4|230
LY-317615|PAK3|4300
LY-317615|PCTK1|5300
LY-317615|PDGFRB|3300
LY-317615|PFTAIRE2|4900
LY-317615|PFTK1|1500
LY-317615|PHKG1|4200
LY-317615|PIM1|200
LY-317615|PIM2|870
LY-317615|PIM3|1100
LY-317615|PIP5K1C|6600
LY-317615|PKAC-alpha|330
LY-317615|PKAC-beta|590
LY-317615|PKN1|5100
LY-317615|PRKCD|25
LY-317615|PRKCE|8.9
LY-317615|PRKCH|46
LY-317615|PRKCQ|36
LY-317615|PRKG1|1100
LY-317615|PRKG2|170
LY-317615|RPS6KA4(Kin.Dom.1-N-terminal)|2500
LY-317615|RPS6KA5(Kin.Dom.1-N-terminal)|370
LY-317615|RSK1(Kin.Dom.1-N-terminal)|1600
LY-317615|RSK2(Kin.Dom.1-N-terminal)|87
LY-317615|RSK3(Kin.Dom.1-N-terminal)|220
LY-317615|RSK4(Kin.Dom.1-N-terminal)|25
LY-317615|S6K1|1800
LY-317615|SLK|3100
LY-317615|SNARK|4100
LY-317615|STK16|2500
LY-317615|STK33|4900
LY-317615|TLK1|510
LY-317615|TLK2|1400
LY-317615|TNK1|3400
LY-317615|YSK4|1600
clear
Select Highlight spots color from Pallette:
(also used in table view)
Tree Image Options
Restore default options
Spot options:
IndianRed
PaleGreen
Gold
PowderBlue
Fill?
Outline?
Outline thickness:
1
2
3
4
5
Select Spots Color from Pallette:
(spot highlight color below)
micro
nano
Spot Size:
Scaling Factor:
.1
.2
.3
.4
.5
.6
.7
.8
.9
1
1.1
1.2
1.3
Area increase factor:
100%
90%
80%
70%
60%
50%
(per change of 10x Kd or 10% Competition)
Legend options:
Left align Text
Right align Text
Label options:
Compound Name?
Compound Name Font:
.5
1
1.5
2
Show Assay Panel information?
Show Panel Spots?
Append Concentration? (i.e., 'AB500@1000nm'; check before loading.)
Background Image:
Target labels?
Dark Tree Branch image?
Hide Lipid, Mutant, ATypical and Pathogen?
Spot options:
Spot Color transparency level:
none
low
medium-low
medium
high
no color
Spot Cutoff Value:
Kd (nM) (Blank for no cutoff)
Spot outline only?
Format:
JPEG(200KB per image)
Publication Quality(5MB image)
Create Publication Quality (5MB bitmap) Image for:
Select Compound
LY-317615
size/quality
100
90
80
70
60
50
40
30
% of original
White Space Border:
Yes
No
Preview and Highlighting
Highlight an assay by clicking on the spot or checking the box next to the Gene Symbol Name.
Click 'Update' to create the new images.
Compound To Highlight:
None
LY-317615
Highlight Panel?
* WildType kinase assays appear in both the main TREEspot and Mutant kinase dendrogams.
Human Kinome image created by KINOMEscan.
2 images created. To download (copy and paste) all images to your local machine click Open/Browse Image Folder.
Images Saved To:
D:\Eurofins\PROD\Applications\FrontOffice_Discovery\StudyManagement\TreeSpot\HTSTools\TreeImages\667_v3hacdhl0jusasilyk2b53bg\
Open/Browse Image Folder
View Options:
(These options do not modify the images that have been created, only the view on this page)
LY-317615
Legend
Show Selected
Size:
Select Size
small
medium
full size
Images per Row:
1
Legend Resize?
Hover the cursor to identify spots and click to highlighted it. To save an image click the Zoom/Download link.
Zoom/Download
Highlight
Locate an Assay
AAK1
AKT3
BIKE
CAMK2D
CDK3
CDK7
CDK9
CLK1
CLK2
CLK4
DMPK
DRAK1
DYRK1A
DYRK1B
ERK8
FLT3
FLT3
GRK1
GRK7
GSK3B
HIPK1
HIPK2
HIPK4
HPK1
ICK
JAK3(JH1domain-catalytic)
MET
MET
MST2
MYLK4
PFTK1
PIM1
PIM2
PIM3
PKAC-alpha
PKAC-beta
PRKCD
PRKCE
PRKCH
PRKCQ
PRKG1
PRKG2
RPS6KA4(Kin.Dom.1-N-terminal)
RPS6KA5(Kin.Dom.1-N-terminal)
RSK1(Kin.Dom.1-N-terminal)
RSK2(Kin.Dom.1-N-terminal)
RSK3(Kin.Dom.1-N-terminal)
RSK4(Kin.Dom.1-N-terminal)
S6K1
STK16
TLK1
TLK2
YSK4
Legend
Data Table View:
Show All Data
Only Selected Compounds/Trees
TREE
spot
Copyright © 2005-2012 KINOMEscan, a division of DiscoveRx Corp. All Rights Reserved.