Ubiquitin

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  • 23-021 - UBE1 Protein, active, 10 ug $162.00 Add To Cart Qty:
    UBE1 catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. It is responsible for the primary ubiquitin-protein isopeptide bond formation and is a critical component for the initiation...
  • 23-021-K - UBE1 Protein, active
    UBE1 catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. It is responsible for the primary ubiquitin-protein isopeptide bond formation and is a critical component for the initiation...
  • 23-021M - UBE1 Protein, active, 250 ug $893.01 Add To Cart Qty:
    UBE1 catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. It is responsible for the primary ubiquitin-protein isopeptide bond formation and is a critical component for the initiation...
  • 23-022 - UbcH3 Protein, active, 10 ug $143.17 Add To Cart Qty:
    Ubiquitin-conjugating (E2) enzymes are characterized by the presence of a highly conserved ubiquitin-conjugating domain which accommodates ATP-activated ubiquitin (Ub) via a covalently linked thioester onto its active-site...
  • 23-022-K - UbcH3 Protein, active
    Ubiquitin-conjugating (E2) enzymes are characterized by the presence of a highly conserved ubiquitin-conjugating domain which accommodates ATP-activated ubiquitin (Ub) via a covalently linked thioester onto its active-site...
  • 23-022M - UbcH3 Protein, active, 250 ug $682.89 Add To Cart Qty:
    Ubiquitin-conjugating (E2) enzymes are characterized by the presence of a highly conserved ubiquitin-conjugating domain which accommodates ATP-activated ubiquitin (Ub) via a covalently linked thioester onto its active-site...
  • 23-023 - SCF-Skp2 Protein Complex, Active, 10 ug $458.35 Add To Cart Qty:
    The SCF (Skp1-Cul1-F-box protein) complexes represent the largest family of ubiquitin-protein ligases and mediate the ubiquitination of a broad spectrum of regulatory and signalling proteins in diverse cellular pathways. The...
  • 23-023-K - SCF-Skp2 Protein Complex, Active
    The SCF (Skp1-Cul1-F-box protein) complexes represent the largest family of ubiquitin-protein ligases and mediate the ubiquitination of a broad spectrum of regulatory and signalling proteins in diverse cellular pathways. The...
  • 23-023M - SCF-Skp2 Protein Complex, Active, 250 ug $2,626.50 Add To Cart Qty:
    The SCF (Skp1-Cul1-F-box protein) complexes represent the largest family of ubiquitin-protein ligases and mediate the ubiquitination of a broad spectrum of regulatory and signalling proteins in diverse cellular pathways. The...
  • 23-024 - p27 Protein complex, activated, 10 ug $458.35 Add To Cart Qty:
    p27 is an important regulator of cell cycle progression, involved in G1 arrest. It is a potent inhibitor of cyclin E1- and cyclin A-CDK2 complexes and a positive regulator of cyclin D-dependent kinases such as CDK4. The...
  • 23-024-K - p27 Protein complex, activated
    p27 is an important regulator of cell cycle progression, involved in G1 arrest. It is a potent inhibitor of cyclin E1- and cyclin A-CDK2 complexes and a positive regulator of cyclin D-dependent kinases such as CDK4. The...
  • 23-024M - p27 Protein complex, activated, 250 ug $2,626.50 Add To Cart Qty:
    p27 is an important regulator of cell cycle progression, involved in G1 arrest. It is a potent inhibitor of cyclin E1- and cyclin A-CDK2 complexes and a positive regulator of cyclin D-dependent kinases such as CDK4. The...
  • 23-025 - UbcH4 Protein, active, 50 ug $143.17 Add To Cart Qty:
    Ubiquitin-conjugating (E2) enzymes are characterized by the presence of a highly conserved ubiquitin-conjugating domain which accommodates ATP-activated ubiquitin (Ub) via a covalently linked thioester onto its active-site...
  • 23-025-K - UbcH4 Protein, active
    Ubiquitin-conjugating (E2) enzymes are characterized by the presence of a highly conserved ubiquitin-conjugating domain which accommodates ATP-activated ubiquitin (Ub) via a covalently linked thioester onto its active-site...
  • 23-025M - UbcH4 Protein, active, 250 ug $682.89 Add To Cart Qty:
    Ubiquitin-conjugating (E2) enzymes are characterized by the presence of a highly conserved ubiquitin-conjugating domain which accommodates ATP-activated ubiquitin (Ub) via a covalently linked thioester onto its active-site...
  • 23-026 - SCF-TrCP1 Protein Complex, Active, 10 ug $458.35 Add To Cart Qty:
    The SCF (Skp1-Cul1-F-box protein) complexes represent the largest family of ubiquitin-protein ligases and mediate the ubiquitination of a broad spectrum of regulatory and signalling proteins in diverse cellular pathways. The...
  • 23-026-K - SCF-TrCP1 Protein Complex, Active
    The SCF (Skp1-Cul1-F-box protein) complexes represent the largest family of ubiquitin-protein ligases and mediate the ubiquitination of a broad spectrum of regulatory and signalling proteins in diverse cellular pathways. The...
  • 23-026M - SCF-TrCP1 Protein Complex, Active, 250 ug $2,626.50 Add To Cart Qty:
    The SCF (Skp1-Cul1-F-box protein) complexes represent the largest family of ubiquitin-protein ligases and mediate the ubiquitination of a broad spectrum of regulatory and signalling proteins in diverse cellular pathways. The...
  • 23-027 - b-catenin Protein, activated, 10 ug $458.35 Add To Cart Qty:
    β-catenin is a multifunctional protein; it is a central component of the cadherin cell adhesion complex, regulating the control of cell adhesion and plays an essential role in the Wingless/Wnt signaling pathway that...
  • 23-027-K - b-catenin Protein, activated
    β-catenin is a multifunctional protein; it is a central component of the cadherin cell adhesion complex, regulating the control of cell adhesion and plays an essential role in the Wingless/Wnt signaling pathway that...
  • 23-027M - b-catenin Protein, activated, 250 ug $2,626.50 Add To Cart Qty:
    β-catenin is a multifunctional protein; it is a central component of the cadherin cell adhesion complex, regulating the control of cell adhesion and plays an essential role in the Wingless/Wnt signaling pathway that...
  • 23-028 - IkBa Protein, activated, 10 ug $458.35 Add To Cart Qty:
    IκBα is a cellular protein that inhibits the transcription factor NF-κB. NF-κB plays a central role in cellular stress and inflammatory responses by controlling cytokine-inducible gene expression and...
  • 23-028-K - IkBa Protein, activated
    IκBα is a cellular protein that inhibits the transcription factor NF-κB. NF-κB plays a central role in cellular stress and inflammatory responses by controlling cytokine-inducible gene expression and...
  • 23-028M - IkBa Protein, activated, 250 ug $2,626.50 Add To Cart Qty:
    IκBα is a cellular protein that inhibits the transcription factor NF-κB. NF-κB plays a central role in cellular stress and inflammatory responses by controlling cytokine-inducible gene expression and...
  • 23-029 - UbcH5a Protein, active, 50 ug $143.17 Add To Cart Qty:
    Ubiquitin-conjugating (E2) enzymes are characterized by the presence of a highly conserved ubiquitin-conjugating domain which accommodates ATP-activated ubiquitin (Ub) via a covalently linked thioester onto its active-site...
  • 23-029-K - UbcH5a Protein, active
    Ubiquitin-conjugating (E2) enzymes are characterized by the presence of a highly conserved ubiquitin-conjugating domain which accommodates ATP-activated ubiquitin (Ub) via a covalently linked thioester onto its active-site...
  • 23-029M - UbcH5a Protein, active, 250 ug $682.89 Add To Cart Qty:
    Ubiquitin-conjugating (E2) enzymes are characterized by the presence of a highly conserved ubiquitin-conjugating domain which accommodates ATP-activated ubiquitin (Ub) via a covalently linked thioester onto its active-site...
  • 23-030 - SCF-Fbw7 Protein Complex, Active, 10 ug $458.35 Add To Cart Qty:
    The SCF (Skp1-Cul1-F-box protein) complexes represent the largest family of ubiquitin-protein ligases and mediate the ubiquitination of a broad spectrum of regulatory and signalling proteins in diverse cellular pathways. The...
  • 23-030-K - SCF-Fbw7 Protein Complex, Active
    The SCF (Skp1-Cul1-F-box protein) complexes represent the largest family of ubiquitin-protein ligases and mediate the ubiquitination of a broad spectrum of regulatory and signalling proteins in diverse cellular pathways. The...
  • 23-030M - SCF-Fbw7 Protein Complex, Active, 250 ug $4,285.71 Add To Cart Qty:
    The SCF (Skp1-Cul1-F-box protein) complexes represent the largest family of ubiquitin-protein ligases and mediate the ubiquitination of a broad spectrum of regulatory and signalling proteins in diverse cellular pathways. The...
  • 23-031 - Cyclin E1 complex, 10 ug $458.35 Add To Cart Qty:
    Cyclin E1 functions as a regulator of the cell cycle, promoting the G1 to S phase transition by binding to and activating the cyclin dependent kinase CDK2. The abundance of cyclin E1 fluctuates during a normal cell cycle and...
  • 23-031-K - Cyclin E1 complex
    Cyclin E1 functions as a regulator of the cell cycle, promoting the G1 to S phase transition by binding to and activating the cyclin dependent kinase CDK2. The abundance of cyclin E1 fluctuates during a normal cell cycle and...
  • 23-031M - Cyclin E1 complex, 250 ug $2,626.50 Add To Cart Qty:
    Cyclin E1 functions as a regulator of the cell cycle, promoting the G1 to S phase transition by binding to and activating the cyclin dependent kinase CDK2. The abundance of cyclin E1 fluctuates during a normal cell cycle and...
  • 23-032 - MDM2/CK1 sigma Protein, active, 10 ug $458.35 Add To Cart Qty:
    MDM2 is an E3 ubiquitin ligase that regulates the turnover of several cellular factors including the p53 tumour suppressor protein and notably MDM2 itself. The suppression of p53 activity by an amplified Mdm2 gene has been...
  • 23-032-K - MDM2/CK1 sigma Protein, active
    MDM2 is an E3 ubiquitin ligase that regulates the turnover of several cellular factors including the p53 tumour suppressor protein and notably MDM2 itself. The suppression of p53 activity by an amplified Mdm2 gene has been...
  • 23-032M - MDM2/CK1 sigma Protein, active, 250 ug $4,411.38 Add To Cart Qty:
    MDM2 is an E3 ubiquitin ligase that regulates the turnover of several cellular factors including the p53 tumour suppressor protein and notably MDM2 itself. The suppression of p53 activity by an amplified Mdm2 gene has been...
  • 23-033 - MDM2 (c-Myc tagged) Protein, active, 10 ug $458.35 Add To Cart Qty:
    MDM2 is an E3 ubiquitin ligase that regulates the turnover of several cellular factors including the p53 tumour suppressor protein and notably MDM2 itself. The suppression of p53 activity by an amplified Mdm2 gene has been...
  • 23-033-K - MDM2 (c-Myc tagged) Protein, active
    MDM2 is an E3 ubiquitin ligase that regulates the turnover of several cellular factors including the p53 tumour suppressor protein and notably MDM2 itself. The suppression of p53 activity by an amplified Mdm2 gene has been...
  • 23-033M - MDM2 (c-Myc tagged) Protein, active, 250 ug $5,162.09 Add To Cart Qty:
    MDM2 is an E3 ubiquitin ligase that regulates the turnover of several cellular factors including the p53 tumour suppressor protein and notably MDM2 itself. The suppression of p53 activity by an amplified Mdm2 gene has been...
  • 23-034 - p53 Protein, 10 ug $458.35 Add To Cart Qty:
    p53 is expressed in a wide variety of tissues and plays a major role in preventing tumour development. It is involved in cell cycle regulation, functioning as a trans-activator to negatively regulate cell division by...
  • 23-034-K - p53 Protein
    p53 is expressed in a wide variety of tissues and plays a major role in preventing tumour development. It is involved in cell cycle regulation, functioning as a trans-activator to negatively regulate cell division by...
  • 23-034M - p53 Protein, 250 ug $4,334.53 Add To Cart Qty:
    p53 is expressed in a wide variety of tissues and plays a major role in preventing tumour development. It is involved in cell cycle regulation, functioning as a trans-activator to negatively regulate cell division by...
  • 23-035 - UbcH5c Protein, active, 10 ug $143.17 Add To Cart Qty:
    Ubiquitin-conjugating (E2) enzymes are characterized by the presence of a highly conserved ubiquitin-conjugating domain which accommodates ATP-activated ubiquitin (Ub) via a covalently linked thioester onto its active-site...
  • 23-035-K - UbcH5c Protein, active
    Ubiquitin-conjugating (E2) enzymes are characterized by the presence of a highly conserved ubiquitin-conjugating domain which accommodates ATP-activated ubiquitin (Ub) via a covalently linked thioester onto its active-site...
  • 23-035M - UbcH5c Protein, active, 250 ug $682.89 Add To Cart Qty:
    Ubiquitin-conjugating (E2) enzymes are characterized by the presence of a highly conserved ubiquitin-conjugating domain which accommodates ATP-activated ubiquitin (Ub) via a covalently linked thioester onto its active-site...
  • 23-036 - UbcH6 Protein, active, 10 ug $213.55 Add To Cart Qty:
    Ubiquitin-conjugating (E2) enzymes are characterized by the presence of a highly conserved ubiquitin-conjugating domain which accommodates ATP-activated ubiquitin (Ub) via a covalently linked thioester onto its active-site...
  • 23-036-K - UbcH6 Protein, active
    Ubiquitin-conjugating (E2) enzymes are characterized by the presence of a highly conserved ubiquitin-conjugating domain which accommodates ATP-activated ubiquitin (Ub) via a covalently linked thioester onto its active-site...
  • 23-036M - UbcH6 Protein, active, 250 ug $682.89 Add To Cart Qty:
    Ubiquitin-conjugating (E2) enzymes are characterized by the presence of a highly conserved ubiquitin-conjugating domain which accommodates ATP-activated ubiquitin (Ub) via a covalently linked thioester onto its active-site...
  • 23-039 - Smad7, 10 ug $458.35 Add To Cart Qty:
    The TGF-β signalling cascade regulates diverse cellular processes, including cell proliferation, differentiation, apoptosis, adhesion and migration. It plays a fundamental role in a number of different physiological and...
  • 23-039-K - Smad7
    The TGF-β signalling cascade regulates diverse cellular processes, including cell proliferation, differentiation, apoptosis, adhesion and migration. It plays a fundamental role in a number of different physiological and...
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